Virulence-inhibitory activity of the degradation product 3-hydroxybutyrate explains the protective effect of poly-β-hydroxybutyrate against the major aquaculture pathogen Vibrio campbellii [PDF]
Scientific Reports, 2018 The bacterial storage compound poly-β-hydroxybutyrate, a polymer of the short-chain fatty acid 3-hydroxybutyrate, has been reported to protect various aquatic animals from bacterial disease. In order to obtain a better mechanistic insight, we aimed to (1)
Tom Defoirdt +2 more
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Preparation and Characterization of Porous Scaffolds Based on Poly(3-hydroxybutyrate) and Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [PDF]
Life, 2021 Poly(hydroxyalkanoates) (PHAs) with different material properties, namely, the homopolymer poly(3-hydroxybutyrate), P(3HB), and the copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate, P(3HB-co-3HV), with a 3HV of 25 wt.%, were used for the preparation
Asiyah Esmail +7 more
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Poly(3-hydroxybutyrate) and Poly(3-hydroxybutyrate-co-3-hydroxyvalerate): Structure, Property, and Fiber [PDF]
International Journal of Polymer Science, 2014 Poly(3-hydroxybutyrate) [P(3HB)] and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)] are produced by various microorganisms as an intracellular carbon and energy reserve from agricultural feedstocks such as sugars and plant oils under ...
Qingsheng Liu +3 more
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Enantiomer‐Specific Cardiovascular Effects of the Ketone Body 3‐Hydroxybutyrate [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground The ketone body 3‐hydroxybutyrate (3‐OHB) increases cardiac output (CO) by 35% to 40% in healthy people and people with heart failure. The mechanisms underlying the effects of 3‐OHB on myocardial contractility and loading conditions as well as
Nigopan Gopalasingam +15 more
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Versatile sugar and valerate metabolic pathways in Paraburkholderia xenovorans LB400 enable tailored poly(3-hydroxybutyrate-co-3-hydroxyvalerate) production [PDF]
Applied Microbiology and BiotechnologyPoly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) polymers are accumulated by diverse prokaryotes. Their distinct monomer compositions enable their use as tailored bioplastics.
Mario I. Sepúlveda +10 more
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Physiological medium and 3-hydroxybutyrate modulate autophagy-linked organelle remodeling in human external urethral sphincter myoblasts [PDF]
Scientific ReportsAutophagy-linked organelle remodeling is essential for skeletal muscle differentiation and is closely linked to the metabolic environment. The ketone body 3-hydroxybutyrate (3HB) serves as an alternative energy substrate and signaling molecule that ...
Hironori Kai +4 more
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D,L‐3‐hydroxybutyrate in the treatment of glucose transporter 1 deficiency syndrome (Glut1DS) [PDF]
JIMD ReportsBackground Deficiency of the Glut1 transporter due to mono‐allelic variants in SLC2A1 causes hypoglycorrhachia, resulting in a neurological spectrum from neonatal epilepsy to adult‐onset paroxysmal movement disorders (PMD).
Aya Amer +7 more
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The potential protective effect of 3-Hydroxybutyrate against aortic dissection: a mendelian randomization analysis [PDF]
Nutrition & MetabolismBackground 3-Hydroxybutyrate, also called β-hydroxybutyrate, is a significant constituent of ketone bodies. Previous observational and experimental studies have suggested that ketogenic diet, especially 3-hydroxybutyrate, may have a protective effect ...
Shi Qiu +5 more
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A Phasin with Many Faces: Structural Insights on PhaP from Azotobacter sp. FA8 [PDF]
, 2014 Phasins are a group of proteins associated to granules of polyhydroxyalkanoates (PHAs). Apart from their structural role as part of the PHA granule cover, different structural and regulatory functions have been found associated to many of them, and ...
Bucci, Hernán Andrés +5 more
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Production and Characterization of Melt-Spun Poly(3-hydroxybutyrate)/Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) Blend Monofilaments [PDF]
ACS OmegaSabrina Kopf +5 more
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