Results 1 to 10 of about 815,133 (291)

Oxaloacetate and Ketone Bodies Synergistically Promote Myoblast Differentiation in L6 Cells [PDF]

Molecules
Malnutrition and aging are major factors that inhibit myoblast differentiation, leading to a decline in muscle function and contributing to sarcopenia development.
Yuji Onuki, Naoki Nanashima, Yutaro Sasaki, Akiko Kojima-Yuasa, Toshio Norikura   +4 more
doaj   +3 more sources

Regulation of adult stem cell function by ketone bodies [PDF]

Frontiers in Cell and Developmental Biology, 2023
Adult stem cells play key roles in tissue homeostasis and regeneration. Recent evidence suggests that dietary interventions can significantly impact adult stem cell function. Some of these effects depend on ketone bodies. Adult stem cells could therefore
Ole Emil Andersen, Ole Emil Andersen, Jens Vase Poulsen, Jean Farup, Jean Farup, Antoine de Morree   +5 more
doaj   +2 more sources

Ketone Bodies in Cardiovascular Disease [PDF]

JACC: Basic to Translational Science
Summary: Evidence for the potential of ketone bodies (KBs) in the treatment of cardiovascular disease is growing rapidly. In addition to serving as sources of myocardial fuel, KBs exert an array of pleiotropic activities via multiple mechanisms.
Azariyas A. Challa, MD, PhD, Bradford G. Hill, PhD, Matthew A. Nystoriak, PhD, Kara R. Gouwens, BS, Dinesh K. Kalra, MD   +4 more
doaj   +2 more sources

Early Detection of Elevated Ketone Bodies in Type 1 Diabetes Using Insulin and Glucose Dynamics Across Age Groups: Model Development Study [PDF]

JMIR Diabetes
BackgroundDiabetic ketoacidosis represents a significant and potentially life-threatening complication of diabetes, predominantly observed in individuals with type 1 diabetes (T1D).
Simon Cichosz, Clara Bender
doaj   +2 more sources

Ketone Bodies after Cardiac Arrest: A Narrative Review and the Rationale for Use [PDF]

Cells
Cardiac arrest survivors suffer the repercussions of anoxic brain injury, a critical factor influencing long-term prognosis. This injury is characterised by profound and enduring metabolic impairment.
Filippo Annoni, Elisa Gouvea Bogossian, Lorenzo Peluso, Fuhong Su, Anthony Moreau, Leda Nobile, Stefano Giuseppe Casu, Elda Diletta Sterchele, Lorenzo Calabro, Michele Salvagno, Mauro Oddo, Fabio Silvio Taccone   +11 more
doaj   +2 more sources

Ketone Bodies Preserve Mitochondria Through Epigenetics∗ [PDF]

JACC: Basic to Translational Science, 2023
Risa Mukai, PhD, Junichi Sadoshima, MD, PhD   +1 more
doaj   +2 more sources

Ketone bodies and the heart

Archives of Medical Science – Atherosclerotic Diseases, 2021
Ketone bodies are low chain organic substances with four carbon atoms, with β-hydroxybutyric acid and acetone being the main ketone bodies in blood circulation. Under physiological conditions their levels are low while during conditions of oxidative stress, such as exercise, fasting state and acute illness, ketone body levels are increased.
Papazafiropoulou, Athanasia K., Georgopoulos, Maximos M., Katsilambros, Nikolaos L.   +2 more
openaire   +2 more sources

Urine ketone bodies and adverse outcomes in patients with acute ischemic stroke or TIA

Atherosclerosis Plus, 2022
Background and aims: Urine ketone bodies have been considered as predictors of stroke in diabetic patients, however, the role of urine ketone bodies in the prognosis of stroke has not been investigated well.
Anxin Wang, Xue Tian, Yingting Zuo, Qin Xu, Xia Meng, Pan Chen, Hao Li, Yongjun Wang   +7 more
doaj   +1 more source

Beta-Hydroxybutyrate: A Dual Function Molecular and Immunological Barrier Function Regulator

Frontiers in Immunology, 2022
Ketone bodies are crucial intermediate metabolites widely associated with treating metabolic diseases. Accumulating evidence suggests that ketone bodies may act as immunoregulators in humans and animals to attenuate pathological inflammation through ...
Jiancheng Qi, Linli Gan, Jing Fang, Jizong Zhang, Xin Yu, Hongrui Guo, Dongjie Cai, Hengmin Cui, Liping Gou, Junliang Deng, Zhisheng Wang, Zhicai Zuo   +11 more
doaj   +1 more source

Editorial: Ketone bodies: friend or foe? [PDF]

Frontiers in Endocrinology
Felix Sternberg, Felix Sternberg, Mitsunori Nomura, Min Xie, Kalina Duszka, Kalina Duszka   +5 more
doaj   +2 more sources