Results 21 to 30 of about 815,133 (291)

Diminished ketone interconversion, hepatic TCA cycle flux, and glucose production in D-β-hydroxybutyrate dehydrogenase hepatocyte-deficient mice

open access: yesMolecular Metabolism, 2021
Objective: Throughout the last decade, interest has intensified in intermittent fasting, ketogenic diets, and exogenous ketone therapies as prospective health-promoting, therapeutic, and performance-enhancing agents.
David B. Stagg   +6 more
doaj   +1 more source

Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons?

open access: yesNeural Regeneration Research, 2018
Glucose is the main energy substrate for neurons, however, at certain conditions, e.g. in starvation, these cells could also use ketone bodies. This approach is used in clinical conditions as the ketogenic diet.
Sergei V Fedorovich   +2 more
doaj   +1 more source

Ketone bodies : back to a place in the sun.

open access: yes, 2021
Ketone bodies have a strong negative image in medicine because of ketoacidosis, a life-threatening complication in diabetes. However, Fang et al. report that ketone bodies exert antisenescent effects in podocytes under diabetic conditions, via activation
久米, 真司   +4 more
core   +1 more source

Determination of 14C radioactivity in ketone bodies: a new, simplified method and its validation.

open access: yesJournal of Lipid Research, 1980
A rapid and reproducible method for the assay of 14C radioactivity in ketone bodies is described, based on the heat lability of acetoacetate and the ability of beta-hydroxybutyrate to quantitatively bind to and elute from an ion exchange resin. Potential
J M Miles   +3 more
doaj   +1 more source

Impact of ketogenic diet and ketone diester supplementation on body weight, blood glucose, and ketones in Sprague Dawley rats fed over two weeks

open access: yesFood Chemistry: Molecular Sciences, 2021
Ketogenic diets consist of low carbohydrate/high fat, shifting energy reliance from glucose to ketone bodies. Ketone diester supplement to a standard diet (ketone ester) increases ketone bodies by adding a substance without altering other consumed foods.
LT Claire M. Modica   +6 more
doaj   +1 more source

Impact of Exercise on the Presence of Urinary Ketones Based on Korea National Health and Nutrition Examination Survey Data, 2014–2015

open access: yesJournal of Obesity & Metabolic Syndrome, 2020
Background : Ketone bodies are a well-known metabolite from the utilization of fatty acids in the fasting state. Some studies have demonstrated the metabolic benefits of urinary ketones in a specific population in whom ketone bodies were detected ...
Jong-Min Han, Nam-Seok Joo
doaj   +1 more source

The Ketone Bridge Between the Heart and the Bladder: How Fast Should We Go? [PDF]

open access: yesInternational Neurourology Journal
Metabolic syndrome (MS) is associated with both cardiovascular and bladder dysfunction. Insulin resistance (IR) and central obesity, in particular, are the main risk factors. In these patients, vicious pathological cycles exacerbate abnormal carbohydrate
Gabriel Faria-Costa   +8 more
doaj   +1 more source

SGLT2 Inhibitors and Ketone Metabolism in Heart Failure

open access: yesJournal of Lipid and Atherosclerosis, 2022
Sodium-glucose cotransporter-2 (SGLT2) inhibitors have emerged as powerful drugs that can be used to treat heart failure (HF) patients, both with preserved and reduced ejection fraction and in the presence or absence of type 2 diabetes.
Huitzilihuitl Saucedo-Orozco   +4 more
doaj   +1 more source

SLC16a6, mTORC1, and Autophagy Regulate Ketone Body Excretion in the Intestinal Cells

open access: yesBiology, 2023
Ketone bodies serve several functions in the intestinal epithelium, such as stem cell maintenance, cell proliferation and differentiation, and cancer growth.
Takashi Uebanso   +5 more
doaj   +1 more source

Ketone Body Metabolism in the Ischemic Heart

open access: yesFrontiers in Cardiovascular Medicine, 2021
Ketone bodies have been identified as an important, alternative fuel source in heart failure. In addition, the use of ketone bodies as a fuel source has been suggested to be a potential ergogenic aid for endurance exercise performance.
Stephen C. Kolwicz
doaj   +1 more source

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