Background : Ketone bodies are a well-known metabolite from the utilization of fatty acids in the fasting state. Some studies have demonstrated the metabolic benefits of urinary ketones in a specific population in whom ketone bodies were detected ...
Jong-Min Han, Nam-Seok Joo
doaj +1 more source
Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E. +5 more
core +1 more source
The Ketone Bridge Between the Heart and the Bladder: How Fast Should We Go? [PDF]
Metabolic syndrome (MS) is associated with both cardiovascular and bladder dysfunction. Insulin resistance (IR) and central obesity, in particular, are the main risk factors. In these patients, vicious pathological cycles exacerbate abnormal carbohydrate
Gabriel Faria-Costa +8 more
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Severity of experimental escherichia-coli mastitis in ketonemic and nonketonemic dairy-cows. [PDF]
The severity of experimental Escherichia coli mastitis in relation to in vitro chemotaxis of polymorphonuclear leukocytes was investigated in cows during negative energy balance. The negative energy balance was induced by feed restriction.
Brand, A +6 more
core +1 more source
SLC16a6, mTORC1, and Autophagy Regulate Ketone Body Excretion in the Intestinal Cells
Ketone bodies serve several functions in the intestinal epithelium, such as stem cell maintenance, cell proliferation and differentiation, and cancer growth.
Takashi Uebanso +5 more
doaj +1 more source
Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase [PDF]
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized.
Ala-Korpela, M +25 more
core +2 more sources
Ketone Bodies Stimulate Chaperone-mediatedAutophagy [PDF]
Chaperone-mediated autophagy (CMA) is a selective lysosomal protein degradative process that is activated in higher organisms under conditions of prolonged starvation and in cell culture by the removal of serum. Ketone bodies are comprised of three compounds (beta-hydroxybutyrate, acetoacetate, and acetone) that circulate during starvation, especially ...
Patrick F, Finn, J Fred, Dice
openaire +2 more sources
Exploring the role of ketone bodies in the diagnosis and treatment of psychiatric disorders
In recent times, advances in the field of metabolomics have shed greater light on the role of metabolic disturbances in neuropsychiatric conditions. The following review explores the role of ketone bodies and ketosis in both the diagnosis and treatment ...
Naomi Elyse Omori +3 more
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Ketone Body Metabolism in the Ischemic Heart
Ketone bodies have been identified as an important, alternative fuel source in heart failure. In addition, the use of ketone bodies as a fuel source has been suggested to be a potential ergogenic aid for endurance exercise performance.
Stephen C. Kolwicz
doaj +1 more source
Pathophysiological Abnormalities in Migraine Ameliorated by Ketosis: A Proof-of-Concept Review
Migraine is a prevalent heterogeneous neurological disorder, enumerated as the eighth most disabling neurological disorder by the World Health Organization.
Panitda Huynh, Pasquale Calabrese
doaj +1 more source

