Results 1 to 10 of about 1,691,805 (269)

Overexpression of SCAP inhibits autophagy and promotes lipid accumulation in vascular smooth muscle cells

open access: yesDi-san junyi daxue xuebao, 2022
Objective To determine the effect of sterol regulatory element binding proteins cleavage activating protein (SCAP) on foam cell formation in vascular smooth muscle cells (VSMCs). Methods LV-SCAP were constructed with LV-SCAP, and LV-Control group served
RAO Yuhan   +4 more
doaj   +1 more source

Clinical Characteristics of Inpatients With New-Onset Diabetes Mellitus in Eastern China: Based on Novel Clustering Analysis

open access: yesFrontiers in Endocrinology, 2022
IntroductionThis study aimed to explore the novel classification of inpatients with new-onset diabetes in Eastern China by the cluster-based classification method and compare the clinical characteristics among the different subgroups.MethodsA total of ...
Xueke Song   +24 more
doaj   +1 more source

CCR5 as a prognostic biomarker correlated with immune infiltrates in head and neck squamous cell carcinoma by bioinformatic study

open access: yesHereditas, 2022
Background C-C chemokine receptor 5 (CCR5) has recently been recognized as an underlying therapeutic target for various malignancies. However, the association of CCR5 with prognosis in the head and neck squamous cell carcinoma (HNSC) patients and tumor ...
Chunhong Li   +10 more
doaj   +1 more source

Subcutaneous glucose measurements and glucose regulation (?) [PDF]

open access: yesIntensive Care Medicine, 2010
Sir: Andrea Stoszkova et al. [1] conclude, based on a correlation coefficient of 0.69 comparing subcutaneous glucose values (Guardian RT) and blood glucose values (Central Laboratory) in 15 patients, that subcutaneous devices should not be used in critically ill patients. However, Holzinger et al.
Ligtenberg, Jack J.   +3 more
openaire   +2 more sources

The association of soluble cluster of differentiation 36 with metabolic diseases: A potential biomarker and therapeutic target

open access: yesPediatric Discovery, 2023
A cluster of differentiation 36 (CD36), also known as fatty acid translocase, plays an important role in developing and progressing metabolic diseases. Soluble CD36 (sCD36), a circulating form of CD36, is identified in human plasma.
Yun Li, Yaxi Chen, Xiong Z. Ruan
doaj   +1 more source

FAM65A as a novel prognostic biomarker in human tumors reveal by a pan-cancer analysis

open access: yesDiscover Oncology, 2021
Background Family with sequence similarity 65 member A (FAM65A), also known as RIPOR1, is differentially expressed between human tumor and non-tumor tissues in kinds of cancers.
Wenken Liang   +9 more
doaj   +1 more source

Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood

open access: yesGenes and Diseases, 2019
Overfeeding in early life is associated with obesity and insulin resistance in adulthood. In the present study, a well-characterized mouse model was used to investigate whether neonatal overfeeding increases susceptibility to the development of non ...
Juan Du   +6 more
doaj   +1 more source

Glucose Allostasis [PDF]

open access: yesDiabetes, 2003
In many organisms, normoglycemia is achieved by a tight coupling of nutrient-stimulated insulin secretion in the pancreatic β-cell (acute insulin response [AIR]) and the metabolic action of insulin to stimulate glucose disposal (insulin action [M]).
Michael, Stumvoll   +4 more
openaire   +2 more sources

Microarray and bioinformatic analysis reveal the parental genes of m6A modified circRNAs as novel prognostic signatures in colorectal cancer

open access: yesFrontiers in Oncology, 2022
BackgroundAccumulating evidences have revealed that the abnormal N6-methyladenosine (m6A) modification is closely associated with the occurrence, development, progression and prognosis of cancer.
Wenken Liang   +10 more
doaj   +1 more source

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