Results 21 to 30 of about 2,358,825 (297)

Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes [PDF]

open access: yes, 2014
Aims/hypothesis: Impaired glucose uptake in skeletal muscle is an important contributor to glucose intolerance in type 2 diabetes. The aspartate protease, beta-site APP-cleaving enzyme 1 (BACE1), a critical regulator of amyloid precursor protein (APP ...
Hamilton, D. Lee   +26 more
core   +1 more source

Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood

open access: yesGenes and Diseases, 2019
Overfeeding in early life is associated with obesity and insulin resistance in adulthood. In the present study, a well-characterized mouse model was used to investigate whether neonatal overfeeding increases susceptibility to the development of non ...
Juan Du   +6 more
doaj   +1 more source

Lifestyle, glucose regulation and the cognitive effects of glucose load in middle-aged adults [PDF]

open access: yes, 2008
Interventions aimed at improving glucose regulatory mechanisms have been suggested as a possible source of cognitive enhancement in the elderly. In particular, previous research has identified episodic memory as a target for facilitation after either ...
Riby, Leigh   +5 more
core   +1 more source

Glucose enhancement of human memory: A comprehensive research review of the glucose memory facilitation effect [PDF]

open access: yes, 2011
The brain relies upon glucose as its primary fuel. In recent years, a rich literature has developed from both human and animal studies indicating that increases in circulating blood glucose can facilitate cognitive functioning.
Riby, Leigh   +10 more
core   +1 more source

Artificial neural network algorithm for online glucose prediction from continuous glucose monitoring. [PDF]

open access: yes, 2010
Background and Aims: Continuous glucose monitoring (CGM) devices could be useful for real-time management of diabetes therapy. In particular, CGM information could be used in real time to predict future glucose levels in order to prevent hypo ...
Pérez Gandía, Carmen   +15 more
core   +1 more source

Microarray and bioinformatic analysis reveal the parental genes of m6A modified circRNAs as novel prognostic signatures in colorectal cancer

open access: yesFrontiers in Oncology, 2022
BackgroundAccumulating evidences have revealed that the abnormal N6-methyladenosine (m6A) modification is closely associated with the occurrence, development, progression and prognosis of cancer.
Wenken Liang   +10 more
doaj   +1 more source

Glucose enhancement of memory is modulated by trait anxiety in healthy adolescent males [PDF]

open access: yes, 2011
Glucose administration is associated with memory enhancement in healthy young individuals under conditions of divided attention at encoding. While the specific neurocognitive mechanisms underlying this ‘glucose memory facilitation effect’ are currently ...
Michael A Smith   +10 more
core   +1 more source

GLUT2, glucose sensing and glucose homeostasis [PDF]

open access: yesDiabetologia, 2014
The glucose transporter isoform GLUT2 is expressed in liver, intestine, kidney and pancreatic islet beta cells, as well as in the central nervous system, in neurons, astrocytes and tanycytes. Physiological studies of genetically modified mice have revealed a role for GLUT2 in several regulatory mechanisms.
openaire   +3 more sources

Glucose Allostasis [PDF]

open access: yesDiabetes, 2003
In many organisms, normoglycemia is achieved by a tight coupling of nutrient-stimulated insulin secretion in the pancreatic β-cell (acute insulin response [AIR]) and the metabolic action of insulin to stimulate glucose disposal (insulin action [M]).
Michael, Stumvoll   +4 more
openaire   +2 more sources

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