Results 21 to 30 of about 1,691,805 (269)

Research update on the effects of probiotic supplementation during pregnancy on pregnancy complications: a systematic literature review

Zhongguo gonggong weisheng
A growing body of research suggests a correlation between probiotic supplementation during pregnancy and the prevention and treatment of pregnancy complications.
Jing YANG, Xiaochuan WANG, Borui LIU, Xiaoyan ZHANG, Xiaoyu GAO, Jiajin HU   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Therapeutic nutrition strategies for the shared pathophysiology of obesity and sleep-disordered breathings

Nutrition Journal
Sleep-disordered breathings (SDBs) represent both a significant complication and exacerbating factor of obesity, creating a bidirectional relationship that worsens insulin resistance and metabolic dysfunction.
Chunzhuo Xu, Jing Wen, Mengjiao Guo, Jian Zhang, Chen Sun, Xu Liu, Zhaojie Meng, Yang Yu, Deliang Wen   +8 more
doaj   +1 more source

Association between fungal dysbiosis in the first 1 000 days of life and childhood diseases – a review of research progress

Zhongguo gonggong weisheng
Bacteria, as the major component of the human microbiome, have been shown to play important physiological roles in human health and disease development.
Xiaoyan ZHANG, Xiaochuan WANG, Borui LIU, Jing YANG, Xiaoyu GAO, Jiajin HU   +5 more
doaj   +1 more source

Identification and Spatial Visualization of Dysregulated Bile Acid Metabolism in High-Fat Diet-Fed Mice by Mass Spectral Imaging

Frontiers in Nutrition, 2022
Changes in overall bile acid (BA) levels and specific BA metabolites are involved in metabolic diseases, gastrointestinal, and liver cancer. BAs have become established as important signaling molecules that enable fine-tuned inter-tissue communication ...
Qi Zhang, Qi Zhang, Zhen-Hua Wu, Zhen-Hua Wu, Zhen-Hua Wu, Shan-Shan Zhao, Shan-Shan Zhao, Shan-Shan Zhao, Jing Yang, Jing Yang, Jing Yang, Lei Chen, Lei Chen, Lei Chen, Xiao-Yu Wang, Xiao-Yu Wang, Xiao-Yu Wang, Zhan-You Wang, Hui-Xin Liu, Hui-Xin Liu, Hui-Xin Liu   +20 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A systemic review on association between on maternal atmospheric pollution exposure during pregnancy and childhood obesity

环境与职业医学
BackgroundMaternal atmospheric pollution during pregnancy may alter fetal intrauterine development programming, thereby increasing the risk of childhood obesity in the future.ObjectiveTo investigate the effects of atmospheric pollution exposure during ...
Lu ZHENG, Borui LIU, Ningyu WAN, Xiaochuan WANG, Zhe YANG, Jiajin HU   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

AI-derived constrained conditional model for screening marker genes through integrated high-throughput transcriptome big data

BMC Medical Research Methodology
Currently, a large volume of high-throughput transcriptome data are accessible through various public databases. This brings urgent need to integrate transcriptome data sourced from numerous independent studies to extract common characteristics to ...
Xiaobei Zhou, Jing Wan, Na Lv, Wensu Liu
doaj   +1 more source

Abnormal whole-brain voxelwise structure-function coupling and its association with cognitive dysfunction in patients with different cerebral small vessel disease burdens

Frontiers in Aging Neuroscience, 2023
Cerebral small vessel disease (CSVD) is a universal neurological disorder in older adults that occurs in connection with cognitive dysfunction and is a chief risk factor for dementia and stroke.
Xinyue Zhang, Changhu Liang, Na Wang, Yuanyuan Wang, Yian Gao, Chaofan Sui, Haotian Xin, Mengmeng Feng, Lingfei Guo, Hongwei Wen   +9 more
doaj   +1 more source