Results 41 to 50 of about 3,131,430 (309)

Association between fungal dysbiosis in the first 1 000 days of life and childhood diseases – a review of research progress

open access: yesZhongguo gonggong weisheng
Bacteria, as the major component of the human microbiome, have been shown to play important physiological roles in human health and disease development.
Xiaoyan ZHANG   +5 more
doaj   +1 more source

The Role of Branched-Chain Amino Acids and Branched-Chain α-Keto Acid Dehydrogenase Kinase in Metabolic Disorders

open access: yesFrontiers in Nutrition, 2022
Branched-chain amino acids (BCAAs), composed of leucine, isoleucine, and valine, are important essential amino acids in human physiology. Decades of studies have revealed their roles in protein synthesis, regulating neurotransmitter synthesis, and the ...
Chuang Du   +16 more
doaj   +1 more source

Absorption spectroscopy of glucose based on a silicon photonics evanescent sensor [PDF]

open access: yes, 2013
We present a silicon photonics evanescent sensor for glucose absorption spectroscopy. The important design aspects of this miniature sensor are discussed as well as the experimental challenges. We demonstrate detection of glucose down to 14 mmol/L, close
Baets, Roel   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A systemic review on association between on maternal atmospheric pollution exposure during pregnancy and childhood obesity

open access: yes环境与职业医学
BackgroundMaternal atmospheric pollution during pregnancy may alter fetal intrauterine development programming, thereby increasing the risk of childhood obesity in the future.ObjectiveTo investigate the effects of atmospheric pollution exposure during ...
Lu ZHENG   +5 more
doaj   +1 more source

Improved Self-Control Associated with Using Relatively Large Amounts of Glucose: Learning Self-Control Is Metabolically Expensive [PDF]

open access: yes, 2012
The current study examined whether changes in glucose during a self-control task would predict changes in self-control performance later on. Participants attended two experimental sessions, spaced two weeks apart.
Gailliot, Matthew T.
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Glucose Variability [PDF]

open access: yesDiabetes, 2013
The proposed contribution of glucose variability to the development of the complications of diabetes beyond that of glycemic exposure is supported by reports that oxidative stress, the putative mediator of such complications, is greater for intermittent as opposed to sustained hyperglycemia.
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Sleep Disturbances and Glucose Metabolism in Older Adults: The Cardiovascular Health Study. [PDF]

open access: yes, 2015
ObjectiveWe examined the associations of symptoms of sleep-disordered breathing (SDB), which was defined as loud snoring, stopping breathing for a while during sleep, and daytime sleepiness, and insomnia with glucose metabolism and incident type 2 ...
Biggs, Mary Lou   +10 more
core   +2 more sources

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