Results 41 to 50 of about 5,325,641 (318)
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy [PDF]
Background: Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect.
Stefan Walenta +26 more
core +1 more source
Ketogenesis takes place in hepatocyte mitochondria where acetyl-CoA derived from fatty acid catabolism is converted to ketone bodies (KB), namely β-hydroxybutyrate (β-OHB), acetoacetate and acetone. KB represent important alternative energy sources under
V. Spigoni +7 more
semanticscholar +1 more source
1H NMR studies of urine during fasting: excretion of ketone bodies and acetylcarnitine [PDF]
High-resolution 1H NMR spectroscopy has been applied to a study of urine from five normal human subjects during a 48-h period of fasting and for 22 h thereafter.
Sadler, P.J. +3 more
core +1 more source
Objective: Throughout the last decade, interest has intensified in intermittent fasting, ketogenic diets, and exogenous ketone therapies as prospective health-promoting, therapeutic, and performance-enhancing agents.
David B. Stagg +6 more
doaj +1 more source
Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics
Ketone body metabolism is a central node in physiological homeostasis. In this review, we discuss how ketones serve discrete fine-tuning metabolic roles that optimize organ and organism performance in varying nutrient states, and protect from ...
Patrycja Puchalska, P. Crawford
semanticscholar +1 more source
Ketone bodies – causes and effects of their increased presence in cows’ body fluids: A review
Ketosis is the most common metabolic disease in high-performance dairy cows during the first 6-8 weeks of lactation. Its main symptoms include an excessive amount of so-called ketone bodies in a cow’s body fluids.
P. Guliński
semanticscholar +1 more source
unigenes associated with synthesis and degradation of ketone ...
Karen Fugate (480954)
core +1 more source
Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons?
Glucose is the main energy substrate for neurons, however, at certain conditions, e.g. in starvation, these cells could also use ketone bodies. This approach is used in clinical conditions as the ketogenic diet.
Sergei V Fedorovich +2 more
doaj +1 more source
unigenes associated with synthesis and degradation of ketone bodies
Karen Fugate (480954)
core +1 more source
Determination of 14C radioactivity in ketone bodies: a new, simplified method and its validation.
A rapid and reproducible method for the assay of 14C radioactivity in ketone bodies is described, based on the heat lability of acetoacetate and the ability of beta-hydroxybutyrate to quantitatively bind to and elute from an ion exchange resin. Potential
J M Miles +3 more
doaj +1 more source

