Results 41 to 50 of about 5,325,641 (318)

Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy [PDF]

open access: yes, 2011
Background: Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect.
Stefan Walenta   +26 more
core   +1 more source

Activation of G protein-coupled receptors by ketone bodies: Clinical implication of the ketogenic diet in metabolic disorders

open access: yesFrontiers in Endocrinology, 2022
Ketogenesis takes place in hepatocyte mitochondria where acetyl-CoA derived from fatty acid catabolism is converted to ketone bodies (KB), namely β-hydroxybutyrate (β-OHB), acetoacetate and acetone. KB represent important alternative energy sources under
V. Spigoni   +7 more
semanticscholar   +1 more source

1H NMR studies of urine during fasting: excretion of ketone bodies and acetylcarnitine [PDF]

open access: yes, 1986
High-resolution 1H NMR spectroscopy has been applied to a study of urine from five normal human subjects during a 48-h period of fasting and for 22 h thereafter.
Sadler, P.J.   +3 more
core   +1 more source

Diminished ketone interconversion, hepatic TCA cycle flux, and glucose production in D-β-hydroxybutyrate dehydrogenase hepatocyte-deficient mice

open access: yesMolecular Metabolism, 2021
Objective: Throughout the last decade, interest has intensified in intermittent fasting, ketogenic diets, and exogenous ketone therapies as prospective health-promoting, therapeutic, and performance-enhancing agents.
David B. Stagg   +6 more
doaj   +1 more source

Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics

open access: yesCell Metabolism, 2017
Ketone body metabolism is a central node in physiological homeostasis. In this review, we discuss how ketones serve discrete fine-tuning metabolic roles that optimize organ and organism performance in varying nutrient states, and protect from ...
Patrycja Puchalska, P. Crawford
semanticscholar   +1 more source

Ketone bodies – causes and effects of their increased presence in cows’ body fluids: A review

open access: yesVeterinary World, 2021
Ketosis is the most common metabolic disease in high-performance dairy cows during the first 6-8 weeks of lactation. Its main symptoms include an excessive amount of so-called ketone bodies in a cow’s body fluids.
P. Guliński
semanticscholar   +1 more source

ketone bodies-png [PDF]

open access: yes, 2014
unigenes associated with synthesis and degradation of ketone ...
Karen Fugate (480954)
core   +1 more source

Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons?

open access: yesNeural Regeneration Research, 2018
Glucose is the main energy substrate for neurons, however, at certain conditions, e.g. in starvation, these cells could also use ketone bodies. This approach is used in clinical conditions as the ketogenic diet.
Sergei V Fedorovich   +2 more
doaj   +1 more source

ketone bodies-html [PDF]

open access: yes, 2014
unigenes associated with synthesis and degradation of ketone bodies  
Karen Fugate (480954)
core   +1 more source

Determination of 14C radioactivity in ketone bodies: a new, simplified method and its validation.

open access: yesJournal of Lipid Research, 1980
A rapid and reproducible method for the assay of 14C radioactivity in ketone bodies is described, based on the heat lability of acetoacetate and the ability of beta-hydroxybutyrate to quantitatively bind to and elute from an ion exchange resin. Potential
J M Miles   +3 more
doaj   +1 more source

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