Results 41 to 50 of about 57,304 (300)

Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms

Frontiers in Neurology, 2019
There is growing evidence that ketone bodies, which are derived from fatty acid oxidation and usually produced in fasting state or on high-fat diets have broad neuroprotective effects.
Huajun Yang, Huajun Yang, Wei Shan, Wei Shan, Wei Shan, Wei Shan, Fei Zhu, Fei Zhu, Jianping Wu, Jianping Wu, Jianping Wu, Qun Wang, Qun Wang, Qun Wang, Qun Wang   +14 more
doaj   +1 more source

Ketogenic diet-induced weight loss is associated with an increase in vitamin d levels in obese adults [PDF]

, 2019
Vitamin D is an important micronutrient involved in several processes. Evidence has shown a strong association between hypovitaminosis D and cardio-metabolic diseases, including obesity.
Gigliotti, S, Maio, R, Perticone, F., Perticone, M, Pinto, A, Pujia, R, Sciacqua, A, Sesti, G, Suraci, E, Zito, R   +9 more
core   +1 more source

Pharmacometabolomics reveals racial differences in response to atenolol treatment. [PDF]

, 2013
Antihypertensive drugs are among the most commonly prescribed drugs for chronic disease worldwide. The response to antihypertensive drugs varies substantially between individuals and important factors such as race that contribute to this heterogeneity ...
Beitelshees, Amber L, Boyle, Stephen, Chapman, Arlene B, Churchill, Erik, Cooper-Dehoff, Rhonda M, Fiehn, Oliver, Frye, Reginald F, Gong, Yan, Johnson, Julie A, Kaddurah-Daouk, Rima, Pharmacometabolomics Research Network, Wikoff, William R, Zhu, Hongjie   +12 more
core   +2 more sources

Efficacy of modified atkins ketogenic diet in chronic cluster headache. An open-label, single-arm, clinical trial [PDF]

, 2018
Introduction: Drug-resistant cluster headache (CH) is still an open clinical challenge. Recently, our group observed the clinical efficacy of a ketogenic diet (KD), usually adopted to treat drug-resistant epilepsies, on migraine.
Cherubino Di Lorenzo, Davide Di Lenola, Francesco Pierelli, Francesco Pierelli, Gianluca Coppola, Giorgio Di Lorenzo, Giulio Sirianni, Mariano Serrao, Maurizio Evangelista, Paolo Rossi   +9 more
core   +3 more sources

Characteristics of Cardiac Ketone Body Metabolism Throughout the Life Cycle

Cardiovascular Therapeutics
Ketone bodies can serve as energy substrates for the heart and perform important molecular signal transduction functions. In recent years, the therapeutic potential of ketone bodies has become a research hotspot in the field of cardiovascular diseases ...
Lei Li, Xiaojian Song, Xiurui Ma, Yanwu Xu   +3 more
doaj   +1 more source

Elevated Plasma Levels of Ketone Bodies Are Associated With All‐Cause Mortality and Incidence of Heart Failure in Older Adults: The CHS

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Chronic disease, such as heart failure, influences cellular metabolism and shapes circulating metabolites. The relationships between key energy metabolites and chronic diseases in aging are not well understood. This study aims to determine the
Sebastian Niezen, Margery A. Connelly, Calvin Hirsch, Jorge R. Kizer, Maria E. Benitez, Scott Minchenberg, Maria Camila Perez‐Matos, Zhenghui Gordon Jiang, Kenneth J. Mukamal   +8 more
doaj   +1 more source

Starvation of Cancer via Induced Ketogenesis and Severe Hypoglycemia

, 2014
Neoplasms are highly dependent on glucose as their substrate for energy production and are generally not able to catabolize other fuel sources such as ketones and fatty acids.
Kapelner, Adam, Vorsanger, Matthew
core   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Relationships between milk ketone bodies and selected milk indicators during conventional and extended lactation [PDF]

Journal of Central European Agriculture
During lactation, dairy cows undergo various metabolic changes that are reflected not only in milk yield but also in milk composition. This study aimed to determine the milk performance and composition depending on the stage of lactation and describe ...
Karolína REINDL, Lucie HASOŇOVÁ, Roman KONEČNÝ, Michaela HORČIČKOVÁ, Jan TRÁVNÍČEK, Natalia CLIMOVA, Simona JANOUŠEK HONESOVÁ, Martin KVÁČ, Jindřich ČÍTEK, Oto HANUŠ, Eva SAMKOVÁ   +10 more
doaj   +1 more source

Additive Manufacturing of Continuous Fibre Reinforced Composites: Process, Characterisation, Modelling, and Sustainability

Advanced Engineering Materials, EarlyView.
Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley   +1 more source