Results 41 to 50 of about 845,184 (295)

Exploring the role of ketone bodies in the diagnosis and treatment of psychiatric disorders

Frontiers in Psychiatry, 2023
In recent times, advances in the field of metabolomics have shed greater light on the role of metabolic disturbances in neuropsychiatric conditions. The following review explores the role of ketone bodies and ketosis in both the diagnosis and treatment ...
Naomi Elyse Omori, Mantas Kazimieras Malys, Geoffrey Woo, Latt Mansor   +3 more
doaj   +1 more source

ketone bodies-html

, 2014
unigenes associated with synthesis and degradation of ketone bodies  
Karen Fugate (480954)
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Characteristics of Cardiac Ketone Body Metabolism Throughout the Life Cycle

Cardiovascular Therapeutics
Ketone bodies can serve as energy substrates for the heart and perform important molecular signal transduction functions. In recent years, the therapeutic potential of ketone bodies has become a research hotspot in the field of cardiovascular diseases ...
Lei Li, Xiaojian Song, Xiurui Ma, Yanwu Xu   +3 more
doaj   +1 more source

Effects of ketogenic diet and ketone bodies on the cardiovascular system: Concentration matters

, 2020
International audienceKetone bodies have emerged as central mediators of metabolic health, and multiple beneficial effects of a ketogenic diet, impacting metabolism, neuronal pathologies and, to a certain extent, tumorigenesis, have been reported both in
Biesiekierska, M., Pirola, L., Balcerczyk, A., Vialichka, V., Nasser, S.   +4 more
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Relationships between milk ketone bodies and selected milk indicators during conventional and extended lactation [PDF]

Journal of Central European Agriculture
During lactation, dairy cows undergo various metabolic changes that are reflected not only in milk yield but also in milk composition. This study aimed to determine the milk performance and composition depending on the stage of lactation and describe ...
Karolína REINDL, Lucie HASOŇOVÁ, Roman KONEČNÝ, Michaela HORČIČKOVÁ, Jan TRÁVNÍČEK, Natalia CLIMOVA, Simona JANOUŠEK HONESOVÁ, Martin KVÁČ, Jindřich ČÍTEK, Oto HANUŠ, Eva SAMKOVÁ   +10 more
doaj   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Elevated Plasma Levels of Ketone Bodies Are Associated With All‐Cause Mortality and Incidence of Heart Failure in Older Adults: The CHS

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Chronic disease, such as heart failure, influences cellular metabolism and shapes circulating metabolites. The relationships between key energy metabolites and chronic diseases in aging are not well understood. This study aims to determine the
Sebastian Niezen, Margery A. Connelly, Calvin Hirsch, Jorge R. Kizer, Maria E. Benitez, Scott Minchenberg, Maria Camila Perez‐Matos, Zhenghui Gordon Jiang, Kenneth J. Mukamal   +8 more
doaj   +1 more source