Results 61 to 70 of about 845,184 (295)

The Role of Exogenous Ketones in Road Cycling: Evidence, Mechanisms, and Performance Claims

open access: yesPhysiologia
Background: Ketone body supplementation has emerged as a potential ergogenic aid in cycling. Exogenous ketones, primarily in the form of beta-hydroxybutyrate, offer an alternative fuel source, bypassing the need for strict ketogenic diets.
Sebastian Sitko
doaj   +1 more source

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

open access: yesAdvanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne   +12 more
wiley   +1 more source

Ketone Bodies and The Atkins Diet

open access: yes, 2021
Ketogenic diet, while usually adopted for its substantial weight loss results, has several other applications in the medical field. Ketone bodies have been observed to lessen the severity and frequency of epileptic seizures, reduce effects of other ...
Bryd, Sierra
core   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

open access: yesAdvanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen   +7 more
wiley   +1 more source

Ketone Bodies Inhibit the Opening of Acid-Sensing Ion Channels (ASICs) in Rat Hippocampal Excitatory Neurons in vitro

open access: yesFrontiers in Neurology, 2019
Objectives: Despite the long-term efficacy of antiepileptic drug treatments, frequent attacks of drug-resistant epilepsy necessitate the development of new antiepileptic drug therapy targets.
Fei Zhu   +18 more
doaj   +1 more source

Ketone body metabolism in ascorbic acid deficiency: in vivo utilization of ketone bodies in guinea pigs

open access: yes, 1959
Blood and urinary levels of ketone bodies were studied in normal, ascorbic acid-deficient, and pair-fed control, guinea pigs. The resting levels of ketone bodies in the blood and urine throughout the course of ascorbic acid-deficiency do not differ ...
Albert F. Debons   +3 more
core   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas   +6 more
wiley   +1 more source

Ketone bodies upregulate endothelial connexin 43 (Cx43) gap junctions

open access: yes, 2014
Ketosis occurs as a metabolic consequence of negative energy balance in post-calving lactating dairycows. Metabolism of free fatty acids, released from adipose tissue, generates excessive amounts of acetoacetate(AcAc), b-hydroxybutyrate (BHB), and ...
Kun-Wei Chan   +5 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

open access: yesAdvanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait   +7 more
wiley   +1 more source

Very‐low‐carbohydrate diet enhances human T‐cell immunity through immunometabolic reprogramming

open access: yesEMBO Molecular Medicine, 2021
Very‐low‐carbohydrate diet triggers the endogenous production of ketone bodies as alternative energy substrates. There are as yet unproven assumptions that ketone bodies positively affect human immunity.
Simon Hirschberger   +14 more
doaj   +1 more source

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