Results 71 to 80 of about 815,133 (291)

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

open access: yesAdvanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen   +12 more
wiley   +1 more source

Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral Infections [PDF]

open access: yes, 2020
Respiratory viral infections remain a scourge, with seasonal influenza infecting millions and killing many thousands annually and viral pandemics, such as COVID-19, recurring every decade.
Koutnik, Andrew P   +6 more
core   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan   +14 more
wiley   +1 more source

Ketone Bodies and Acute Energy Compensation in Women Following Exercise

open access: yes, 2022
Acute EC (energy compensation) can occur following an exercise session in women. In recent years, the popularity of ketogenic diets or exogenous ketone bodies has drastically increased, namely due to their appetite sensation suppressive effect.
Duquet, Miryam
core   +1 more source

Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control

open access: yesAdvanced Science, EarlyView.
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang   +9 more
wiley   +1 more source

Ketone body, as an emerging modulator of metabolic reprogramming and epigenetics in breast cancer [PDF]

open access: yesIranian Journal of Basic Medical Sciences
The metabolic profile of cancer cells, notably their reliance on glucose as a primary energy source for proliferation, sets them apart from normal cells. This metabolic dependency may significantly affect their invasive potential when an adequate glucose
Fatemeh Mehdikhani   +4 more
doaj   +1 more source

Scalable Crackle‐Lithography for Multifunctional Enclosed Plastic Nanofluidic Devices

open access: yesAdvanced Science, EarlyView.
Crackle‐lithography enables scalable fabrication of enclosed plastic‐substrate‐based nanofluidic devices with interconnected nanochannels that enable molecular transport, optical interrogation, confined electroless copper deposition, and ionic memristive behavior.
Tirumala Rao Dumpala   +8 more
wiley   +1 more source

Detection of Subclinical Ketosis in Dairy Cows [PDF]

open access: yesPakistan Veterinary Journal, 2012
Ketosis is a common metabolic disorder frequently observed in dairy cows during the early lactation period. It is characterized by increased levels of ketone bodies in the blood, urine, and milk.
Zhigang Zhang, Guowen Liu1, Hongbin Wang, Xiaobing Li1 and Zhe Wang1*
doaj  

Metabolic Effects of the Very-Low-Carbohydrate Diets: Misunderstood "Villains" of Human Metabolism

open access: yesJournal of the International Society of Sports Nutrition, 2004
During very low carbohydrate intake, the regulated and controlled production of ketone bodies causes a harmless physiological state known as dietary ketosis. Ketone bodies flow from the liver to extra-hepatic tissues (e.g., brain) for use as a fuel; this
Manninen Anssi H
doaj   +1 more source

Hydrophobic modification of poly(aryl ether ketone ketone) aerogel via poly(dimethylsiloxane)

open access: yes, 2017
Property and structure of aerogels with polar groups almost suffer from their high hydrophilicity. In this study, in order to improve the hydrophobicity of poly(aryl ether ketone ketone) aerogel prepared from poly(aryl ether ketone ketone) containing ...
He, Liu   +5 more
core   +1 more source

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