Results 91 to 100 of about 815,133 (291)

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Role of ketone bodies in perinatal myocardial energy metabolism

open access: yes, 2001
Metabolic changes at around the time of birth are crucial for life. Here we review the energy utilization in the myocardium, emphasizing ketone body metabolism. Before birth, glucose and lactate are the major energy substrates for the myocardium.
Kuipers, JRG   +2 more
core   +1 more source

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

open access: yesAdvanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria   +5 more
wiley   +1 more source

Structures of the ketone bodies

open access: yes, 1997
These are the structures of the ketone bodies. Acetoacetate and beta-hydroxybutyrate are important physiological substrates. Acetone is a byproduct, and is not metabolized further.

core  

Discovery of the Cyclic Form of MRI pH‐Sensor Z‐OMPD Enables >5% 13C Hyperpolarization by SABRE

open access: yesAngewandte Chemie International Edition, EarlyView.
With “c‐OMPD”, we discovered a previously unknown 5‐membered lactol structure that arises from the homoaldol condensation of the central metabolite pyruvic acid. We demonstrate that the cyclization equilibrium is of crucial importance for OMPD's function as MRI‐based pH sensor and achieve for the first time 13C polarization levels (>5%) by SABRE in the
Juanita Ferreira   +9 more
wiley   +1 more source

Hypothalamic sensing of ketone bodies after prolonged cerebral exposure leads to metabolic control dysregulation

open access: yes, 2016
Ketone bodies have been shown to transiently stimulate food intake and modify energy homeostasis regulatory systems following cerebral infusion for a moderate period of time (
Fioramonti, X.   +13 more
core   +1 more source

Stabilization of PUFA‐Rich Mayonnaise Against Lipid Oxidation: A Review of the Last Three Decades of Research

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Mayonnaise, a widely consumed oil‐in‐water emulsion, is highly susceptible to lipid oxidation due to its high content of polyunsaturated fatty acids (PUFAs) and the presence of pro‐oxidant factors such as low pH and iron from egg yolk. Over the past three decades, extensive research has focused on understanding oxidation mechanisms, analytical
Sakhi Ghelichi   +2 more
wiley   +1 more source

Plasma–Kinetic Coupling and Redox Mechanisms in the Degradation of Acid Red 51 by Atmospheric Corona Discharge

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study investigates the degradation of the xanthene dye Acid Red 51 (ARE‐51) using atmospheric‐pressure corona discharge plasma, integrating electrical characterization, optical emission spectroscopy (OES), kinetic modeling, and physicochemical analysis to establish a unified plasma–liquid interaction framework. A degradation efficiency of
Cristian Mendoza Benítez   +7 more
wiley   +1 more source

Metabolism of ketone bodies by ovine brain in vivo

open access: yes, 1976
Ketosis was produced by intravenous infusion (5 mmol/kg per h) of [3-14C]acetoacetate (sp act 0.5 muCi/mmol) into fed and 7-day-fasted sheep. Changes in arterial and sagittal sinus blood samples.
RG Kammula
core   +1 more source

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