Results 81 to 90 of about 845,184 (295)

Detection of Subclinical Ketosis in Dairy Cows [PDF]

open access: yesPakistan Veterinary Journal, 2012
Ketosis is a common metabolic disorder frequently observed in dairy cows during the early lactation period. It is characterized by increased levels of ketone bodies in the blood, urine, and milk.
Zhigang Zhang, Guowen Liu1, Hongbin Wang, Xiaobing Li1 and Zhe Wang1*
doaj  

Metabolic Effects of the Very-Low-Carbohydrate Diets: Misunderstood "Villains" of Human Metabolism

open access: yesJournal of the International Society of Sports Nutrition, 2004
During very low carbohydrate intake, the regulated and controlled production of ketone bodies causes a harmless physiological state known as dietary ketosis. Ketone bodies flow from the liver to extra-hepatic tissues (e.g., brain) for use as a fuel; this
Manninen Anssi H
doaj   +1 more source

Hypothalamic sensing of ketone bodies after prolonged cerebral exposure leads to metabolic control dysregulation

open access: yes, 2016
Ketone bodies have been shown to transiently stimulate food intake and modify energy homeostasis regulatory systems following cerebral infusion for a moderate period of time (
Fioramonti, X.   +20 more
core   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan   +14 more
wiley   +1 more source

A Water Compartment Cell Culture Lid Enables Stable Longitudinal Recording of Neuronal Networks In Vitro

open access: yesAdvanced Science, EarlyView.
A cell culture lid with an integrated water compartment eliminates evaporation from microelectrode arrays while preserving gas exchange. Freed from the osmotic drift and repeated medium exchanges that disturb conventional recordings, patterned human iPSC‐derived neuronal networks are recorded continuously for five weeks. Single‐spike resolution reveals
Benedikt Maurer   +4 more
wiley   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng   +7 more
wiley   +1 more source

Structures of the ketone bodies

open access: yes, 1997
These are the structures of the ketone bodies. Acetoacetate and beta-hydroxybutyrate are important physiological substrates. Acetone is a byproduct, and is not metabolized further.

core  

When are Two‐Dimensional Covalent Organic Frameworks Good Electrodes for Lithium Ion Batteries? A Data‐Driven Analysis

open access: yesAdvanced Science, EarlyView.
A data‐driven framework integrating density‐functional theory with machine learning models screens two‐dimensional covalent organic frameworks (2D COFs) from CoRE COF database to reveal atomic‐level design rules: N/O‐rich coordination pockets drive cathode behavior, while separated redox sites and π‐rich galleries enable anode function in Li‐ion ...
Preeti Bhauriyal   +2 more
wiley   +1 more source

Electrochemical and Thermal Interplay in Blended Cathodes for All Solid‐State Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This work analyzes blended LFP‐NMC cathodes for all solid state batteries, revealing their balanced rate performance and enhanced thermal properties. Operando X‐ray diffraction studies uncovered lithiation gradients and asymmetric charging effects due to kinetic limitations.
Simon Si Ming Ji   +17 more
wiley   +1 more source

Ketone bodies and islet function: 86Rb handling and metabolic data.

open access: yes, 1990
The metabolism of ketone bodies was investigated in rat pancreatic islets incubated in the absence or presence of D-glucose. The generation of 14CO2 from 3-14C-labeled ketone bodies, the interconversion of D-(-)-beta-hydroxybutyrate and acetoacetate ...
Yilmaz, T   +16 more
core   +1 more source

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