Results 81 to 90 of about 57,304 (300)

A comparison of the satiating properties of medium-chain triglycerides and conjugated linoleic acid in participants with healthy weight and overweight or obesity [PDF]

, 2020
Purpose Inconsistent evidence exists for greater satiety after medium-chain triglycerides (MCT) or conjugated linoleic acid (CLA) compared to long-chain triglycerides (LCT).
Clegg, Miriam E., Deleuse, Martina, Maher, Tyler, Shafat, Amir, Thondre, Sangeetha   +4 more
core   +2 more sources

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Ketone body, as an emerging modulator of metabolic reprogramming and epigenetics in breast cancer [PDF]

Iranian Journal of Basic Medical Sciences
The metabolic profile of cancer cells, notably their reliance on glucose as a primary energy source for proliferation, sets them apart from normal cells. This metabolic dependency may significantly affect their invasive potential when an adequate glucose
Fatemeh Mehdikhani, Sadegh Rajabi, Maryam Mohammadlou, Marc Maresca, Rasoul Baharlou   +4 more
doaj   +1 more source

The depolarizing action of GABA in cultured hippocampal neurons is not due to the absence of ketone bodies. [PDF]

PLoS ONE, 2011
Two recent reports propose that the depolarizing action of GABA in the immature brain is an artifact of in vitro preparations in which glucose is the only energy source. The authors argue that this does not mimic the physiological environment because the
Jaylyn Waddell, Jimok Kim, Bradley E Alger, Margaret M McCarthy   +3 more
doaj   +1 more source

Alterations in the mitochondrial proteome of neuroblastoma cells 2 in response to complex 1 inhibition [PDF]

, 2011
Increasing evidence points to mitochondrial dysfunction in Parkinson's disease (PD) associated with complex I dysfunction, but the exact pathways which lead to cell death have not been resolved.
Billett, EE, Burté, F, De Girolamo, LA, Hargreaves, AJ   +3 more
core   +1 more source

Ketone Bodies as Anti-Seizure Agents [PDF]

Neurochemical Research, 2017
There is growing evidence that ketone bodies (KB)-derived from fatty acid oxidation and produced during fasting or consumption of high-fat diets-can exert broad neuroprotective effects. With respect to epilepsy, KB (such as β-hydroxybutyrate or BHB, acetoacetate and acetone) have been shown to block acutely induced and spontaneous recurrent seizures in
Simeone, Timothy A, Simeone, Kristina A, Rho, Jong M   +2 more
openaire   +4 more sources

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Metabolic Effects of the Very-Low-Carbohydrate Diets: Misunderstood "Villains" of Human Metabolism

Journal of the International Society of Sports Nutrition, 2004
During very low carbohydrate intake, the regulated and controlled production of ketone bodies causes a harmless physiological state known as dietary ketosis. Ketone bodies flow from the liver to extra-hepatic tissues (e.g., brain) for use as a fuel; this
Manninen Anssi H
doaj   +1 more source

Indocyanine green elimination test in orthotopic liver recipients. [PDF]

, 1996
OBJECTIVE: To determine its predictive capability on graft quality and resultant clinical outcome, the indocyanine green (ICG) elimination test was performed by a spectrophotometric method and a noninvasive finger-piece method with 50 orthotopic liver ...
Demetris, AJ, Jabbour, N, Mizoe, A, Starzl, TE, Todo, S, Tsubono, T, Warty, V   +6 more
core   +1 more source

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source