Results 151 to 160 of about 18,900,322 (326)

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort   +8 more
wiley   +1 more source

Insights from a 6‐year hair drug analysis compendium in drug‐facilitated sexual assault cases

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Drug‐facilitated sexual assault (DFSA) may involve a diverse array of substances, including illicit drugs, prescription medications, and over‐the‐counter pharmaceuticals. Hair analysis has emerged as a valuable forensic tool, offering an extended window of detection spanning several months. However, interpreting drug concentrations in hair can
Amandine Fort   +8 more
wiley   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

The effect of gamma radiation on mechanical properties of biodegradable polymers poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate)

open access: yesMaterials Research, 2013
Brazilian poly(3-hydroxybutyrate), P(3-HB), and its copolymer, poly (3-hydroxybutyrate-co-3-hydroxyvalerate), P(3-HB-co-3-HV) were irradiated with gamma radiation (60Co) at room temperature and in the presence of oxygen. The viscosity-average molar mass (
Leticia Maria Oliveira   +2 more
doaj  

What anabolic–androgenic steroids reveal about the limits of current harm reduction models

open access: yesAddiction, EarlyView.
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski   +2 more
wiley   +1 more source

3-Hydroxybutyrate alleviates septic liver injury by promoting macrophage polarization from M1 to M2

open access: yes生物医学转化
Objective To investigate the therapeutic effects and underlying mechanisms of the metabolite 3- hydroxybutyrate (3HB) in a cecal ligation and puncture (CLP)-induced sepsis model in mice.
Hu Jingjuan   +7 more
doaj   +1 more source

High temporal resolution monitoring of illicit drug consumption across England via wastewater analysis

open access: yesAddiction, EarlyView.
Abstract Aim To monitor community‐level consumption of 20 illicit drugs across urban areas of England using wastewater‐based epidemiology (WBE) surveillance at high temporal resolution. Design, setting, cases This study was conducted over a 12‐month period in 2022 sampling 24‐hour composite wastewater samples at 15 wastewater treatment plants (WWTPs ...
Helena Rapp‐Wright   +14 more
wiley   +1 more source

Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects

open access: yesFrontiers in Nutrition
IntroductionThe brain uses ketones, mainly 3-hydroxybutyrate (3-HB), as an alternative energy source. Therefore, oral intake of 3-HB may help maintain brain health.
Kentaro Nishioka   +12 more
doaj   +1 more source

‘Emptiness filled with love’: A reflexive thematic analysis of chemsex trajectories among gay, bisexual and other men who have sex with men in Almaty, Kazakhstan, using a life course framework

open access: yesAddiction, EarlyView.
Abstract Background and aims The intentional use of psychoactive substances to enhance sexual experiences, known as chemsex, is associated with human immunodeficiency virus (HIV) transmission, psychological distress and social isolation among gay, bisexual and other men who have sex with men (GBMSM).
Nikolay Lunchenkov   +3 more
wiley   +1 more source

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