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Synthesis of 2-Fluoroacetoacetic Acid and 4-Fluoro-3-hydroxybutyric Acid

Synthesis, 2019
The butyric acid scaffold is the base structure of several human metabolites that serve diverse and prominent biochemical roles including as oxidative sources of cellular energy and as substrates for biosynthesis.
S. Mattingly, F. Wuest, R. Schirrmacher
semanticscholar   +1 more source

4-Benzoylamino-3-hydroxybutyric Acid, Historically First “Anomalous Racemate”: Reinvestigation

Crystal Growth & Design, 2015
Chiral 4-benzoylamino-3-hydroxybutyric acid (1) was recognized in 1930 as the first example of “anomalous racemates” (correct to say, anomalous conglomerates), that is, specific addition compounds formed by different enantiomers in unequal ratio. Through the comparative (racemic against homochiral samples) inspection of the IR spectra, single crystal X-
Alexander A. Bredikhin   +4 more
openaire   +1 more source

Biosynthesis of enantiopure (S)-3-hydroxybutyric acid in metabolically engineered Escherichia coli

Applied Microbiology and Biotechnology, 2008
A biosynthetic pathway for the production of (S)-3-hydroxybutyric acid (S3HB) from glucose was established in recombinant Escherichia coli by introducing the beta-ketothiolase gene from Ralstonia eutropha H16, the (S)-3-hydroxybutyryl-CoA dehydrogenase gene from R.
Lee, SH   +3 more
openaire   +3 more sources

3-Hydroxybutyric Acid Interacts with Lipid Monolayers at Concentrations That Impair Consciousness

Langmuir, 2013
3-Hydroxybutyric acid (also referred to as β-hydroxybutyric acid or BHB), a small molecule metabolite whose concentration is elevated in type I diabetes and diabetic coma, was found to modulate the properties of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) monolayers when added to the subphase at clinical concentrations.
Tienyi T, Hsu   +4 more
openaire   +2 more sources

Telechelic diols from poly[(R)‐3‐hydroxybutyric acid] and poly{[(R)‐3‐hydroxybutyric acid]‐co‐[(R)‐3‐hydroxyvaleric acid]}

Macromolecular Chemistry and Physics, 1996
AbstractWe describe the preparation of telechelic OH‐terminated poly[(R)‐3‐hydroxybutyric acid] (PHB) and poly{[(R)‐3‐hydroxybutyric acid]‐co‐[(R)‐3‐hydroxyvaleric acid]} (PHB/HV), on a semi‐preparative scale, by a transesterification procedure from the high‐molecular weight polymers.
Thomas D. Hirt   +2 more
openaire   +1 more source

Alpha-amylase inhibitor increases plasma 3-hydroxybutyric acid in food-restricted rats

Experientia, 1995
The effect on energy metabolism of delayed absorption of starch by inhibition of alpha-amylase was examined by considering levels of plasma glucose and 3-hydroxybutyric acid (3-OHBA) in rats. Addition of alpha-amylase inhibitor (alpha AI) to a high starch diet delayed the plasma glucose response after feeding: peak plasma glucose levels in the control ...
T, Doi   +6 more
openaire   +2 more sources

Sunflower-based biorefinery: Poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate- co -3-hydroxyvalerate) production from crude glycerol, sunflower meal and levulinic acid

Bioresource Technology, 2014
Polyhydroxybutyrate (PHB) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)] production was developed in bioreactor cultures using the strain Cupriavidus necator DSM 7237 cultivated on crude glycerol, sunflower meal (SFM) hydrolysates and levulinic acid as the sole fermentation feedstocks.
Vasiliki, Kachrimanidou   +6 more
openaire   +2 more sources

Accumulation of 3-hydroxyisobutyric acid, 2-methyl-3-hydroxybutyric acid and 3-hydroxyisovaleric acid in ketoacidosis

Clinica Chimica Acta, 1975
1. Urine and serum samples from patients with ketoacidosis of varying degree and etiology have been examined by gas chromatography and mass spectrometry. 2. In addition to 3-hydroxyisovaleric acid, relatively high concentrations of two analogous hydroxy acids, 3-hydroxyisobutyric acid and 2-methyl-3-hydroxybutyric acid, were found in the urine.
openaire   +2 more sources

Short Synthesis of (R)- and (S)-4-Amino-3-Hydroxybutyric Acid (GABOB)

Synthesis, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
TIECCO, Marcello   +6 more
openaire   +2 more sources

Synthesis and accumulation of poly(3-hydroxybutyric acid) by Rhizobium sp.

Acta Biologica Hungarica, 2000
Forty-two Rhizobium strains obtained from different culture collections were evaluated quantitatively for poly(3-hydroxy-butyric acid) [PHB] production in shake flask culture. The majority of the strains produced the maximum amount of PHB during the late exponential or stationary phase of growth.
A, Manna, S, Pal, A K, Paul
openaire   +2 more sources

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