Results 121 to 130 of about 422,853 (267)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Research Communication: An International Tree-Ring Isotope Data Bank—A Proposed Repository For Tree-Ring Isotopic Data [PDF]

, 2009
The International Tree-Ring Data Bank (ITRDB) is an invaluable resource, providing access to a massive and growing cache of tree-ring data. Oxygen, carbon, nitrogen and hydrogen isotope treering studies, which have provided valuable climatic and ...
Csank, Adam Z.
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Computer Assisted, Independent Observer Verification of Tree-Ring Measurements [PDF]

, 1997
The importance of tree-ring analyses to forestry and other disciplines (e.g., climate and ecology) requires that tree-ring measurements be as accurate as possible.
Grissino-Mayer, Henri D.
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Near-Ring 3-Prima dengan Derivasi Tergeneralisasi [PDF]

, 2018
Pada skripsi ini dibahas mengenai beberapa sifat dari near-ring 3- prima N dengan derivasi tergeneralisasi. Sebuah pemetaan jumlahan F: N -, N disebut derivasi tergeneralisasi pada near-ring 3- prima jika memenuni aksioma tertentu. Syarat agar suatu near-
Maharani, Desvie Eka
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Tree-Ring Dating of Two Log Buildings in Central Texas, USA [PDF]

, 1992
Tree-ring dating was used to develop construction scenarios for two log structures, the Draper and the Fuller buildings. in the Edwards Plateau region of Texas. The Draper building was constructed in 1902-3, and added onto in 1906.
Harlan, Thomas P., Fairchild-Parks, James A.   +1 more
core  

3-Prime Near-rings involving right n-derivations

Boletim da Sociedade Paranaense de Matemática
In this paper we will investigate the commutativity in prime near-rings admitting right n-derivation, which satisfy appropriate algebraic conditions on semigroup ideals of the near-rings.
openaire   +1 more source