Results 101 to 110 of about 343,956 (260)
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Completely 2-primal Ideals in Near-rings [PDF]
, 2016 [[abstract]]We introduce the notion of completely 2-primal ideals in near-rings. We have also introduced strongly completely 2-primal near-rings. An ideal I of a near-ring N is said to be completely 2-primal if the prime radical of I, P(I) is completely ...
Dheena, P., Kumar, G. Satheesh
core
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Fano 3-folds, K3 surfaces and graded rings [PDF]
, 2002 Explicit birational geometry of 3-folds represents a second phase of Mori theory, going beyond the foundational work of the 1980s. This paper is a tutorial and colloquial introduction to the explicit classification of Fano 3-folds (Q-Fano 3-folds), a ...
Reid, Miles +2 more
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
On commutativity in prime Γ-near-rings with symmetric bi-derivations [PDF]
, 2014 In this paper, we investigate the conditions of a prime Γ-near-ring to be commutative by means of symmetric bi-derivations.
Sattarovich, Rakhimov Isamiddin +2 more
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Semigroup ideals with multiplicative semiderivations and commutativity of 3-prime near-rings
, 2022 Summary: In the present paper, we introduce the notion of multiplicative semiderivation and prove some theorems in the setting of a semigroup ideal of a 3-prime near-ring admitting a multiplicative semiderivation. Thereby, it is shown that under appropriate additional hypotheses a near-ring must be a commutative ring.
Raji, Abderrahmane +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source