Results 121 to 130 of about 4,170,992 (325)

Revitalising strong cultural connections and resilience: Co-designing a pilot Elder-led mentorship program for Indigenous mothers in a remote northern community in Alberta, Canada

open access: yesGlobal Public Health
Connecting with traditional knowledge and culture promotes the well-being of Indigenous parents and creates healthy environments for child development. Community Elders in a remote northern community in Alberta, Canada, collaborated with researchers to ...
Stephanie Montesanti   +5 more
doaj   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Multi-stakeholder perspectives of community pharmacies’ extended services in Al Baha province, Saudi Arabia: A qualitative study

open access: yesGlobal Public Health
Community pharmacies have expanded to include new services such as health screenings and medication reviews. However, developing and implementing new applications tends to be challenging and entails comprehensive planning by multiple stakeholders.
Khalid S. Alghamdi   +4 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Young people’s lived sexual and reproductive health citizenship: participation and power of youth in Malawi

open access: yesGlobal Public Health
This qualitative, focused critical ethnographic study explores how young people’s ‘lived SRH citizenship’ and their active roles realising their sexual and reproductive health (SRH) and rights, shape their agency and participation in decision-making in ...
Jannah Wigle   +7 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Prevalence and correlation of workload and musculoskeletal disorders in industrial workers: a cross-sectional study

open access: yesFrontiers in Rehabilitation Sciences
BackgroundMusculoskeletal disorders (MSDs) are a leading cause of disability among industrial workers worldwide, often resulting from excessive physical and mental workload.
Anderson G. Rodríguez-Pulido   +2 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A case study of healthcare services in Lurwaryizo, Mbhashe Local Municipality, Eastern Cape Province

open access: yesGlobal Public Health
As part of the strategy by the local municipal government to improve health services in Lurwaryizo community in Mbhashe Local Municipality in Eastern Cape province of South Africa, an investigation of the current healthcare delivery available to the ...
Chidy Akunwafor   +2 more
doaj   +1 more source

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