Results 201 to 210 of about 8,269,734 (342)

Exploring the Paradoxical Relationship of a Creb 3 Regulatory Factor Missense Variant With Body Mass Index and Diabetes Among Samoans: Protocol for the Soifua Manuia (Good Health) Observational Cohort Study (Preprint)

, 2019
Nicola L. Hawley, Alysa Pomer, Anna C. Rivara, Samantha L. Rosenthal, Rachel L. Duckham, Jenna C. Carlson, Take Naseri, Muagututi‘a Sefuiva Reupena, Melania Selu, Vaimoana Lupematisila, Folla Unasa, Lupesina Vesi, Tracy Fatu, Seipepa Unasa, Kima Faasalele‐Savusa, Abigail Wetzel, Christina Soti‐Ulberg, Angela T. Prescott, Gloria Siufaga, Corina Penaia, Sophie B. To, Lauren C. LaMonica, Viali Lameko, Courtney C. Choy, Scott E. Crouter, Susan Redline, Ranjan Deka, Erin E. Kershaw, Zsolt Urbán, Ryan L. Minster, Daniel E. Weeks, Stephen T. McGarvey   +31 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Quality and safety for Sámi users of health and care services: a cross-sectional study from Norway. [PDF]

Int J Circumpolar Health
Olsen RM, Bojanic I, Hufthammer KO, Devik SA.   +3 more
europepmc   +1 more source

3.G. Round table: What is good public health practice? [PDF]

, 2015

openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Association Between Mediterranean Diet Consumption and the Physical and Mental Components of HRQL in Community-Dwelling Older Adults in Valencia. [PDF]

Nutrients
Pérez-Ros P, Rios-Corral A, Cauli O.
europepmc   +1 more source

Preventing Prediabetes Through Adolescent Health Education: Pathways to Achieving Good Health and Well-Being (SDG 3)

Dewi Prabawati, Lia Natalia
openalex   +2 more sources

Working the system: 3 ways planners can defy the odds to promote good health for all of us

, 2019
Jennifer Kent
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

The occurrence and co-occurrence of conflicts and negative acts and their associations with self-rated health, workability, and life-satisfaction: a cross-sectional study of Swedish school principals. [PDF]

BMC Res Notes
Persson R, Leo U, Håkansson C.
europepmc   +1 more source