Results 201 to 210 of about 8,467,334 (349)

Self-rated health, mental wellbeing, nutrition habits, and their association with morbidity of ischemic heart disease. [PDF]

Front Public Health
Aukstakalniene G, Luksiene D, Tamosiunas A, Sileikiene L, Lesauskaite V.   +4 more
europepmc   +1 more source

Health and the primary prevention of violence against women [PDF]

This position paper focuses on the primary prevention of violence perpetrated by men against women. It develops a position on primary prevention (as distinct from secondary and tertiary interventions).

core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Latent profile analysis of medication adherence in lower extremity deep venous thrombosis-cross-sectional study. [PDF]

PLoS One
Hu N, Li X, Fu F, Xie L, Qi J, Wu P, Li Y, Li YL.   +7 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

An economic analysis of the impact of education on health behaviours and health outcomes in South Africa: a case of Amathole District Municipality and Buffalo City Metropolitan Municipality. [PDF]

Health Econ Rev
Hlafa B, Tsegaye A, Dickson M, Hompashe DM.   +3 more
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

All-cause and cause-specific mortality risk in individuals with eating disorders: systematic review and meta-analysis of relative risk and aggravating or attenuating factors. [PDF]

World Psychiatry
Semchishen SN, Højlund M, Lemaire D, Obeegadoo I, Hammond NG, Frangione B, Ogawa H, Sunderland R, Singh A, Wafy G, Campana M, Sakeah J, Brousseau K, Correll CU, Wagner E, Colman I, Solmi M.   +16 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Self-perceived oral health, general self-efficacy, and their relations to oral health conditions in head and neck cancer patients in Sweden-a prospective observational study. [PDF]

Front Oral Health
Karlsson C, Bohm N, Finizia C, Skoogh Andersson J, Almståhl A.   +4 more
europepmc   +1 more source