Results 261 to 270 of about 4,170,992 (325)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Impact of Postdiagnosis Health Behaviors and Behavior Changes on Prognosis in Colorectal Cancer Patients: Evidence From Real-World Data. [PDF]

Cancer Med
Won D, Baek JY, Park JW, Lee J, Cho S, Shin A.   +5 more
europepmc   +1 more source

The Role of Kamishibai Storytelling Technique in Enhancing Preschool Children’s Understanding and Knowledge of the Adverse Effects of Tobacco: Sustainable Development Goal 3 (SDG) (Good Health and Well-Being)

Noor Afiza Abdul Rani, Nur Azzalia Kamaruzaman, Nur Asniza Ishak, Sulastri Samsudin, Sazaroni Md Rashid, Mohd Fadhli Razali, Balamurugan Tangiisuran   +6 more
openalex   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Knowledge, Attitudes, Practices, and Misconceptions Regarding Vitamins in Blood Metabolism and Anemia Among University Students: A One Center Cross-Sectional Study in Ghana. [PDF]

Health Sci Rep
Donkor DM, Owusu G, Essuon-Sepah V, Asamoah O, Anokye I, Sah AK, Apalebilah S, Adu P, Boachie J.   +8 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Knowledge, Attitude and Practices of Primary School Teachers Towards Oral Health in Mchinji District, Malawi. [PDF]

Clin Cosmet Investig Dent
Kafera G, Kalimbira R, Bagg J, Chimimba PC, Mchenga JM, Bwanali AN, Lubanga AF.   +6 more
europepmc   +1 more source

The Impact of Savory (satureja hortensis l.) on Stability of Refined and Cold-Pressed Sunflower Oil: Contributions to SDG 3 - Good Health and Well-Being

Violeta Ognenoska, Gorica Pavlovska, Maša Knez Marevci, Anka Trajkovska Petkoska, Vesna Rafajlovska   +4 more
openalex   +2 more sources

Key personality and training factors influencing athletes' mental health - based on machine learning. [PDF]

PLoS One
Sun G, Wang J, Zhang S.
europepmc   +1 more source

DESIGNING SPORTS EQUIPMENT RENTAL APPLICATIONS AND BOOKING SPORTS FIELDS TO SUPPORT PUBLIC HEALTH AND SDG 3: GOOD HEALTH AND WELL BEING

Maryani MARYANI, Inayatulloh INAYATULLOH
openalex   +2 more sources