Results 151 to 160 of about 10,459,359 (387)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Journal of Current Southeast Asian Affairs, 2015 A modern conception of oligarchy, which can be housed under an authoritarian regime as easily as it can under a liberal democratic one, can affect our understanding of the potential national political repercussions of extreme inequalities of wealth. This
T. F. Rhoden
doaj
FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.
Proceedings of the National Academy of Sciences of the United States of America, 1975 J. McCann, E. Choi, E. Yamasaki, B. Ames
semanticscholar +1 more source
Journal of Politics in Latin America, 2013 Since the return to democracy, Uruguayan presidents have built cabinets of varying natures (majority and minority coalitions, majority and minority parties).
Daniel Chasquetti
doaj
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
300 Faces In-The-Wild Challenge: database and results
Image and Vision Computing, 2016 Christos Sagonas +4 more
semanticscholar +1 more source
Myanmar in Contemporary Chinese Foreign Policy – Strengthening Common Ground, Managing Differences
Journal of Current Southeast Asian Affairs, 2012 This assessment first briefly examines recent features of China’s approach to foreign affairs, and then examines in greater detail features in China’s approach to relations with its neighbours, especially in Southeast Asia. It does so in order to discern
Robert Sutter
doaj
The Role of the Structural Transformation in Aggregate Productivity [PDF]
We investigate the role of sectoral differences in labor productivity and the process of structural transformation (the secular reallocation of labor across sectors) in accounting for the time path of aggregate productivity across countries.
Diego Restuccia, Margarida Duarte
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source