Results 151 to 160 of about 8,871,631 (366)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

Introduction: The 2013 Malaysian Elections: Business as Usual or Part of a Protracted Transition?

open access: yesJournal of Current Southeast Asian Affairs, 2013
For the time being, the 5 May 2013 Malaysian general election (GE13) has resulted in the preservation of an authoritarian regime that has existed since independence in 1957. Although the opposition won almost 51 per cent of the vote, the ruling coalition
Andreas Ufen
doaj  

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

open access: yesFEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu   +4 more
wiley   +1 more source

JOHN LOCKE AFTER 300 YEARS [PDF]

open access: yes
John Locke was a seminal figure in political philosophy and political economy and this year marks the tercentenary of his death. The paper focuses on the classical liberal interpretation of Locke. In this view, Locke defends individualism, natural rights
Alvey, James E.
core   +1 more source

List pricing and pure strategy outcomes in a Bertrand-Edgeworth duopoly [PDF]

open access: yes, 2003
Non-existence of a pure strategy equilibrium in a Bertrand-Edgeworth duopoly model is analyzed. The standard model is modified to include a list pricing stage and a subsequent price discounting stage. Both firms first simultaneously choose a maximum list
García Díaz, Antón, Kujal, Praveen
core   +2 more sources

Electoral Proximity and the Political Involvement of Bureaucrats: A Natural Experiment in Argentina, 1904

open access: yesJournal of Politics in Latin America, 2016
In this paper, I use a slightly modified version of the Becker–Stigler model of corrupt behavior to explain bureaucratic political involvement. Since bureaucrats prefer higher rewards and not to support losing candidates, we expect them to become ...
Valentín Figueroa
doaj  

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

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