Results 131 to 140 of about 10,786,653 (337)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Introduction: The Massacres of 1965–1966: New Interpretations and the Current Debate in Indonesia

open access: yesJournal of Current Southeast Asian Affairs, 2013
The mass violence which spread across Indonesia following an attempt-ed coup on 1 October 1965 claimed the lives of half a million people and irrevocably changed the lives of millions more.
Annie Pohlman
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Book Review: Shrestha, Omkar Lal, and Aekapol Chongvilaivan (eds), Greater Mekong Subregion: From Geographical to Socio-economic Integration

open access: yesJournal of Current Southeast Asian Affairs, 2014
Book Review of the edited volume: Omkar Lal Shrestha and Aekapol Chongvilaivan (eds) (2013), Greater Mekong Subregion: From Geographical to Socio-economic Integration.
Timotheus J. Krahl
doaj  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

The European Union’s Myanmar Policy: Focused or Directionless?

open access: yesJournal of Current Southeast Asian Affairs, 2015
What is the European Union (EU) trying to achieve in Myanmar? Is the EU speaking with one voice and acting collectively (and does it really matter)? Were the sanctions lifted too early?
Jörn Dosch, Jatswan S. Sidhu
doaj  

ATDRSS 300 MB/S modem program [PDF]

open access: yes
The 300 Mbps modem was developed for direct application to the next generation high data rate Time Division Multiple Access (TDMA) communication system.
Ryan, Carl R.
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

China’s Potential for Economic Coercion in the South China Sea Disputes: A Comparative Study of the Philippines and Vietnam

open access: yesJournal of Current Southeast Asian Affairs, 2012
With tensions rising in the South China Sea, China’s use of its economic leverage over Southeast Asian countries has recently come into focus. With increasing economic and trade ties between China and Southeast Asia, the question being asked is whether ...
Madhu Sudan Ravindran
doaj  

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1975
J. McCann, E. Choi, E. Yamasaki, B. Ames
semanticscholar   +1 more source

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