Results 131 to 140 of about 755,225 (262)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Book Review: Heiduk, Felix (ed.): Security Sector Reform in Southeast Asia: From Policy to Practice
Book Review of the edited volume by Heiduk, Felix (ed.) (2014), Security Sector Reform in Southeast Asia: From Policy to Practice. Basingstoke, Hampshire: Palgrave MacMillan, ISBN 978-0-230-22 896-2, 264 pages.
Leanne-Marie McCarthy-Cotter
doaj
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Resolución Rectoral N° 300/2020. Derogar el Artículo 2° de la Resolución CSDEyVE N° 14/2020
Fil: Rector (R). Universidad Nacional de Río Negro. Río Negro, ArgentinaResolución Rectoral N° 300/2020.
Rector (R)
core
In political science and in development cooperation, civic organisations (COs) under authoritarian rule are usually seen as supporters of processes that move towards democratisation. However, these organisations are sometimes criticised for their support
Jörg Wischermann +2 more
doaj
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
In this paper I examine women survivors’ stories about childbirth and child-raising during the period of mass violence following Indonesia’s 1965 coup, as well as some accounts of abortion during detention.
Annie Pohlman
doaj
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source

