Results 121 to 130 of about 10,786,653 (337)

Governance Obstacles to Geothermal Energy Development in Indonesia

open access: yesJournal of Current Southeast Asian Affairs, 2015
Despite having 40 per cent of the world’s potential for geothermal power production, Indonesia exploits less than five per cent of its own geothermal resources.
Matthew S. Winters, Matthew Cawvey
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Resilience of the Communist Party of Vietnam’s Authoritarian Regime since Doi Moi

open access: yesJournal of Current Southeast Asian Affairs, 2016
Unlike communist parties in the former Soviet Union and Eastern and Central Europe, the Communist Party of Vietnam (CPV) has overcome crises to remain in power for the last 30 years and will most likely continue ruling in the coming decades.
Hai Hong NGUYEN
doaj  

KONSERVASI BANGUNAN BERSEJARAH : Studi Kasus Bangunan Peribadatan di Pulau Bali [PDF]

open access: yes, 2016
Pemerintah Indonesia sebenarnya sangat peduli dengan bidang pelestarian. Indonesia juga tidak dapat menghindari proses globalisasi. Kemudian yang menjadi pertanyaan adalah bagaimanakah mengadakan perubahan menuju masyarakat baru, tetapi tidak tercerabut ...
Runa, I Wayan
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Legislators in Myanmar’s First “Post-Junta” National Parliament (2010–2015): A Sociological Analysis

open access: yesJournal of Current Southeast Asian Affairs, 2014
In an attempt to better grasp the realities of Myanmar’s national legislature, which was formed after the 2010 elections, this paper examines the personal profiles and social backgrounds of its elected and appointed members.
Renaud Egreteau
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

From Top To Bottom (and Back To The Top Again): Federal Spending, Sub-national Coalitions, and Protests in Argentina, 2002–2006 De arriba abajo (y vuelta arriba otra vez). Gasto federal, coaliciones subnacionales y protesta en Argentina, 2002-2006

open access: yesJournal of Politics in Latin America, 2012
Can federal-state relations affect popular protests? Using an extensive dataset measuring local protests in the Argentine provinces (2002–2006), I assess the effects of the president’s and governors’ tactical allocations on the persistence of contentious
Lorena Moscovich
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

From the Editor’s Desk

open access: yesJournal of Current Southeast Asian Affairs, 2010
From the Editor’s Desk. Introduction. Editorial.
Marco Bünte, David Camroux
doaj  

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