Results 151 to 160 of about 11,467,373 (235)

Identification of an Unsaturated Hydroxy Fatty Acid Antitumor Oxylipin from Brown Alga <i>Scytosiphon lomentaria</i>: (<i>E</i>)-6-Hydroxyoctadec-4-enoic Acid (NP-011548). [PDF]

Mar Drugs
Mauceri M, Juhmani AS, Zangrando R, Gallo M, Rizzolio F, Sfriso A, Pizzini S, Roman M, Gambaro A, Granchi C, Tuccinardi T, Forlani G, Sfriso AA.   +12 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

UMPSA dalam kelompok 201–300 terbaik dunia bagi pembangunan mampan [PDF]

PEKAN, 24 Jun 2026 – Universiti Malaysia Pahang Al-Sultan Abdullah (UMPSA) terus mengekalkan reputasinya di persada antarabangsa apabila berjaya berada dalam kelompok 201–300 universiti terbaik dunia menerusi penarafan Times Higher Education (THE ...
Naqiah, Puaad
core  

Safety and tolerability of anti-toll-like receptor 3, monoclonal antibody PRV-300 in patients with moderate-to-severe ulcerative colitis: a randomized phase 1B clinical trial (PULSE). [PDF]

J Crohns Colitis
Pokryszka J, Comer GM, Richmond CA, Leon F, Reinisch W.   +4 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Serum [-2]proPSA as a Candidate Phenotypic Correlate of Molecular Alterations and Prognostic Marker in Metastatic Castration-Resistant Prostate Cancer. [PDF]

Prostate Cancer
Conteduca V, Garofoli M, Bruno G, Landriscina M, Fiorenza M, Polito C, Sirica R, Terracciano D.   +7 more
europepmc   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Neuroprotective effects of <i>Entandrophragma cylindricum</i> (Meliaceae) extract against "Odontol''-induced cognitive and depressive disorders: An integrated HPLC, molecular docking and experimental validation. [PDF]

IBRO Neurosci Rep
Nadège AOA, Espoir AMR, Ronald BAG, Symphorien MT, Marcelle DB, Ulrich NTJ, Désiré DP.   +6 more
europepmc   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source