Results 61 to 70 of about 94,503 (212)

Impaired IgM Memory B Cell Function Is Common in Coeliac Disease but Conjugate Pneumococcal Vaccination Induces Robust Protective Immunity

open access: yesVaccines
Coeliac disease (CD) is associated with hyposplenism, an acquired impairment of spleen function associated with reduced IgM memory B cells and increased susceptibility to serious pneumococcal infection.
Olivia G. Moscatelli   +11 more
doaj   +1 more source

Why are enteric ganglia so small? Role of differential adhesion of enteric neurons and enteric neural crest cells. [v1; ref status: indexed, http://f1000r.es/59q]

open access: yesF1000Research, 2015
The avian enteric nervous system (ENS) consists of a vast number of unusually small ganglia compared to other peripheral ganglia. Each ENS ganglion at mid-gestation has a core of neurons and a shell of mesenchymal precursor/glia-like enteric neural crest
Benjamin N. Rollo   +4 more
doaj   +1 more source

Timing the Parkes Multibeam Pulsars [PDF]

open access: yes, 1999
Measurement of accurate positions, pulse periods and period derivatives is an essential follow-up to any pulsar survey. The procedures being used to obtain timing parameters for the pulsars discovered in the Parkes multibeam pulsar survey are described ...
Bell, J. F.   +8 more
core   +1 more source

Janet Halley and the Art of Status Quo Maintenance [PDF]

open access: yes, 2018
Over the past few years, Janet Halley emerged as one of the most avid critics of campus rape feminist activists, activists who push for the reformulation of university investigative rules to shift the burden of proof from the accuser to the accused ...
Abu-Odeh, Lama
core   +2 more sources

Cytokinin downregulates Photosystem II photochemistry during prolonged darkness in a phytochrome B‐dependent manner

open access: yesNew Phytologist, EarlyView.
Cytokinin–phyB signaling modulates PSII photochemistry during prolonged darkness. Summary Cytokinins (CKs) delay dark‐induced senescence, but how they tune photosynthetic function in darkness remains unclear. We investigated the effects of classical aromatic CK benzylaminopurine and CK‐derived compound 1‐(2‐methoxyethyl)‐3‐(1,2,3‐thiadiazol‐5‐yl)urea ...
Veronika Kábrtová   +14 more
wiley   +1 more source

Dimensions of dace dynamics: temporal variation in abundance and survival of an imperiled desert fish guide habitat restoration

open access: yesRestoration Ecology, EarlyView.
Abstract Introduction Desert fishes are vulnerable to anthropogenic environmental alterations that degrade habitat and reduce water availability, but these same fishes benefit from restoration actions that reverse the causes of decline. Ash Meadows speckled dace (Rhinichthys osculus nevadensis) is a federally endangered minnow endemic to the Mojave ...
Jacob P. Wolff   +5 more
wiley   +1 more source

Engineering Micro–Nanomaterials for Biomedical Translation

open access: yesAdvanced NanoBiomed Research, 2021
Engineered nano–bio interfaces–driven by vertical micro/nanoneedles, nanoparticles, organ‐on‐chip devices, and a diversity of nanosubstrates for mass spectroscopy imaging–are spurring scientific and technological progress, from fundamental to ...
Yaping Chen   +8 more
doaj   +1 more source

The Massive Binary Pulsar J1740-3052

open access: yes, 2002
The young pulsar J1740-3052 is in an 8-month orbit with a companion of at least 11 solar masses. We present multifrequency GBT and Parkes timing observations, and discuss implications for the nature of the companion.
Stairs, I. H.   +6 more
openaire   +2 more sources

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo

open access: yesCell Reports, 2015
The CRISPR/Cas9 technology enables the introduction of genomic alterations into almost any organism; however, systems for efficient and inducible gene modification have been lacking, especially for deletion of essential genes.
Brandon J. Aubrey   +9 more
doaj   +1 more source

Severe Impairment of TNF Post-transcriptional Regulation Leads to Embryonic Death

open access: yesiScience, 2020
Summary: Post-transcriptional regulation mechanisms control mRNA stability or translational efficiency via ribosomes, and recent evidence indicates that it is a major determinant of the accurate levels of cytokine mRNAs. Transcriptional regulation of Tnf
Elise Clayer   +7 more
doaj   +1 more source

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