Results 41 to 50 of about 2,466,814 (376)

MiR-15b and miR-322 inhibit SETD3 expression to repress muscle cell differentiation

Cell Death and Disease, 2019
SETD3 is a member of SET-domain containing methyltransferase family, which plays critical roles in various biological events. It has been shown that SETD3 could regulate the transcription of myogenic regulatory genes in C2C12 differentiation and promote ...
Meng-Jie Zhao, Julan Xie, Wen-Jie Shu, Hong-Yan Wang, Jianping Bi, Wei Jiang, Hai-Ning Du   +6 more
semanticscholar   +1 more source

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan, Stephanie A. Chu, Suvi Häkkinen, Liwen Zhang, David McFall, Jonathan D. Rohrer, Jesse A. Brown, Alex J. Lee, Kristen Fernhoff, Lorenzo Pasquini, Katherine P. Rankin, Maria Luisa Mandelli, Maria Luisa Gorno‐Tempini, Jennifer S. Yokoyama, Virginia E. Sturm, Brian Appleby, Bradford C. Dickerson, Kimiko Domoto‐Reilly, Tatiana Foroud, Daniel H. Geschwind, Nupur Ghoshal, Neill R. Graff‐Radford, Ging‐Yuek Robin Hsiung, Eric J. Huang, Edward Huey, Kejal Kantarci, Irene Litvan, Ian R. Mackenzie, Mario F. Mendez, Chiadi U. Onyike, Leonard Petrucelli, Eliana Marisa Ramos, Erik D. Roberson, Julio C. Rojas, Maria Carmela Tartaglia, Arthur W. Toga, Sandra Weintraub, Leah K. Forsberg, Hilary W. Heuer, Brad F. Boeve, Adam L. Boxer, Howard J. Rosen, Bruce L. Miller, Fermin Moreno, William W. Seeley, Suzee E. Lee, on behalf of the ALLFTD Consortium   +46 more
wiley   +1 more source

MicroRNA-322 (miR-322) and Its Target Protein Tob2 Modulate Osterix (Osx) mRNA Stability [PDF]

Journal of Biological Chemistry, 2013
Osteogenesis depends on a coordinated network of signals and transcription factors such as Runx2 and Osterix. Recent evidence indicates that microRNAs (miRNAs) act as important post-transcriptional regulators in a large number of processes, including osteoblast differentiation.
Gamez Molina, Beatriz, Rodríguez Carballo, Edgardo, Bartrons Bach, Ramon, Rosa López, José Luis, Ventura Pujol, Francesc   +4 more
openaire   +4 more sources

A catalogue of damped Lyman alpha absorption systems and radio flux densities of the background quasars [PDF]

, 2002
We present a catalogue of the 322 damped Lyman alpha absorbers taken from the literature. All damped Lyman alpha absorbers are included, with no selection on redshift or quasar magnitude.
Bertoldi, Bowen, Combes, Combes, D'Odorico, de Bruyn, de la Varga, de Vries, Douglas, Drinkwater, Dzuba, E. Corbelli, Ellison, Fanti, Ge, Ivison, J. K. Webb, Kameno, Kanekar, Kanekar, Kanekar, Klein, Kovalev, Large, Le Brun, Le Brun, Ledoux, Levshakov, Lu, Lucas, M. T. Murphy, Matteucci, Ochsenbein, Omont, Omont, Peng, Petitjean, Petitjean, Péroux, R. Bandiera, Rengelink, S. J. Curran, Srianand, Stepanian, Stickel, Stocke, Teräsranta, V. V. Flambaum, Vladilo, Véron-Cetty, Webb, Webb, Wiklind, Wiklind, Wiklind, Wright, Zhang   +56 more
core   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

The 2004 outburst of BHC H1743-322: analysis of spectral and timing properties using the TCAF solution [PDF]

, 2017
The black hole transient H1743-322 exhibited several outbursts with temporal and spectral variability since its discovery in 1977. These outbursts occur at a quasi-regular recurrence period of around $0.5-2$ years, since its rediscovery in March 2003. We
A. Bhattacharjee, Indrani Banerjee, A. Banerjee, D. Debnath, S. Chakrabarti   +4 more
semanticscholar   +1 more source

Gangs, Guns, and Drugs: Recidivism among Serious, Young Offenders [PDF]

, 2007
The primary goal of this study is to understand the factors that best explain recidivism among a sample of 322 young men aged 17 to 24 years released from prison in a Midwestern state.
Adams, Akers, Anderson, Battin-Pearson, Benda, Blumstein, Braga, Bushway, Chaiken, Clemmer, Coleman, Cook, Cook, Cork, Cox, Decker, Decker, Decker, DeJong, Esbensen, Esbensen, Fagan, Fagan, Flannery, Fleisher, Fowler, Gendreau, Giordano, Glaze, Gottfredson, Griffin, Griffin, Hagan, Hariston, Harrison, Hirschi, Holtfreter, Huebner, Huebner, Huff, Hughes, Kennedy, Klein, Kubrin, Langan, Lattimore, Lattimore, Laub, Laub, Lizotte, Loeber, Lynch, Maltz, Maruna, Maruna, Matsueda, McDevitt, McGarrell, Mumola, Nurse, Olson, Pager, Papachristos, Perkins, Petersilia, Rosenfeld, Sampson, Sampson, Sheley, Shover, Singer, Spohn, Sykes, Uggen, Visher, Visher, Wacquant, Warr, Western, Western, Wintemute, Wright, Wright, Zamble   +83 more
core   +3 more sources

Time Trends and Predictors of Gout Remission Over 6 Years

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K. Stamp, William J. Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source

ESTIMATION OF MASS OF COMPACT OBJECT IN H 1743-322 FROM 2010 AND 2011 OUTBURSTS USING TCAF SOLUTION AND SPECTRAL INDEX–QPO FREQUENCY CORRELATION [PDF]

, 2016
The well-known black hole candidate (BHC) H 1743-322 exhibited temporal and spectral variabilities during several outbursts. The variation of the accretion rates and flow geometry that change on a daily basis during each of the outbursts can be very well
A. A. Molla, S. Chakrabarti, D. Debnath, S. Mondal   +3 more
semanticscholar   +1 more source

Collective Motion of Polarized Dipolar Fermi Gases in the Hydrodynamic Regime [PDF]

, 2010
Recently, a seminal STIRAP experiment allowed the creation of 40K-87Rb molecules in the rovibrational ground state [K.-K. Ni et al., Science 322, 231 (2008)]. In order to describe such a polarized dipolar Fermi gas in the hydrodynamic regime, we work out
Aristeu R. P. Lima, Axel Pelster, P. Ring   +2 more
core   +2 more sources