Results 41 to 50 of about 263,787 (343)

Hydroxychloroquine Associated with Lower Glomerular Filtration Rate Decline in Lupus Nephritis

Arthritis Care &Research, Accepted Article.
Background Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical. Therefore, we analyzed data from our
Shivani Garg, Brad Rovin, Brad C. Astor, Tripti Singh, Fauzia Hollnagel, Megan Kuik, Lexie Kolton, Callie Saric, S. Sam Lim, Christie M. Bartels   +9 more
wiley   +1 more source

MicroRNA-322 (miR-322) and Its Target Protein Tob2 Modulate Osterix (Osx) mRNA Stability [PDF]

Journal of Biological Chemistry, 2013
Osteogenesis depends on a coordinated network of signals and transcription factors such as Runx2 and Osterix. Recent evidence indicates that microRNAs (miRNAs) act as important post-transcriptional regulators in a large number of processes, including osteoblast differentiation.
Gamez Molina, Beatriz, Rodríguez Carballo, Edgardo, Bartrons Bach, Ramon, Rosa López, José Luis, Ventura Pujol, Francesc   +4 more
openaire   +4 more sources

Low‐Activation Compositionally Complex Alloys for Advanced Nuclear Applications—A Review

Advanced Engineering Materials, EarlyView.
Low‐activation compositionally complex alloys (LACCAs) are advanced metallic materials primarily composed of low‐activation elements, offering advantages such as rapid compliance with operational standards and safe recyclability. This review highlights their potential for extreme high‐temperature irradiation environments as structural materials for ...
Yangfan Wang, Hanliang Zhu, Zhiyang Wang, Zhijun Qiu, Xiao Wang, Zengxi Pan, Hongtao Zhu, Mingxing Zhang, Huijun Li   +8 more
wiley   +1 more source

The 2004 outburst of BHC H1743-322: analysis of spectral and timing properties using the TCAF solution [PDF]

, 2017
The black hole transient H1743-322 exhibited several outbursts with temporal and spectral variability since its discovery in 1977. These outbursts occur at a quasi-regular recurrence period of around $0.5-2$ years, since its rediscovery in March 2003. We
A. Bhattacharjee, Indrani Banerjee, A. Banerjee, D. Debnath, S. Chakrabarti   +4 more
semanticscholar   +1 more source

Improving Surface Quality of Titanium Electrodeposition from a Deep Eutectic Solvent with Organic and Inorganic Additives

Advanced Engineering Materials, EarlyView.
Herein, the electroplating of titanium from an organic solvent, ethaline, is shown. Polymer additives are shown to smooth the roughness of the film, and small molecule additives are shown to produce a near‐mirror finish to the deposited metal. Titanium electroreduction is desired for a variety of medical, electronic, and bonding applications but has ...
Steven Livers, Christopher Chancellor, Katarzyna Grubel, Diana Horangic, Riah Burnett, Bailey Byrd, Christina Arendt, Lance Hubbard   +7 more
wiley   +1 more source

Tomographic reflection modelling of quasi-periodic oscillations in the black hole binary H 1743-322 [PDF]

, 2016
Accreting stellar mass black holes (BHs) routinely exhibit Type-C quasi-periodic oscillations (QPOs). These are often interpreted as Lense–Thirring precession of the inner accretion flow, a relativistic effect whereby the spin of the BH distorts the ...
A. Ingram, M. Klis, M. Middleton, D. Altamirano, P. Uttley   +4 more
semanticscholar   +1 more source

Self‐Poled Halide Perovskite Ruddlesden‐Popper Ferroelectric‐Photovoltaic Semiconductor Thin Films and Their Energy Harvesting Properties

Advanced Functional Materials, EarlyView.
Low‐dimensional halide perovskite thin films, (BA)2(MA)n‐1PbnBr3n+1 (n = 1, 2), exhibit both semiconducting and ferroelectric properties, enabling mechanical and light energy harvesting. Using Cr/Cr₂O₃ or PCBM as barrier layers ensures reproducible ferroelectricity.
Raja Sekhar Muddam, Shaoyang Wang, Nirmal Prashanth Maria Joseph Raj, Qingping Wang, Philip Wijesinghe, Julia Payne, Matthew S. Dyer, Chris Bowen, Lethy Krishnan Jagadamma   +8 more
wiley   +1 more source

miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy

Genes & Development, 2017
In this study, Rodriguez-Barrueco et al. analyzed ∼3000 primary tumors and show that miR-424(322)/503 is commonly lost in a subset of aggressive breast cancers; they then describe the genetic aberrations that inactivate its expression.
R. Rodríguez-Barrueco, Erin A Nekritz, F. Bertucci, Jiyang Yu, Felix Sanchez-Garcia, Tizita Z. Zeleke, A. Gorbatenko, D. Birnbaum, E. Ezhkova, C. Cordon-Cardo, P. Finetti, David Llobet-Navás, Jose M. Silva   +12 more
semanticscholar   +1 more source

ESTIMATION OF MASS OF COMPACT OBJECT IN H 1743-322 FROM 2010 AND 2011 OUTBURSTS USING TCAF SOLUTION AND SPECTRAL INDEX–QPO FREQUENCY CORRELATION [PDF]

, 2016
The well-known black hole candidate (BHC) H 1743-322 exhibited temporal and spectral variabilities during several outbursts. The variation of the accretion rates and flow geometry that change on a daily basis during each of the outbursts can be very well
A. A. Molla, S. Chakrabarti, D. Debnath, S. Mondal   +3 more
semanticscholar   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source