From abnormality detection to decision-grade deployment: Strengthening the next translational step for DeepCXR. [PDF]
Vijayasimha M, Jha RK, Chakraborty M.
europepmc +1 more source
Aim Pancreatic enzyme replacement therapy (PERT) is essential for the management of pancreatic exocrine insufficiency. Since June 2023, the United Kingdom has been affected by a global shortage of PERT. We investigated the impact of this shortage on national prescribing trends for Creon, Nutrizym, Pancrex and Pangrol.
Teena S. Varghese +6 more
wiley +1 more source
Correction: Renal coccidiosis in black skimmers in North America reveals an uncharacterized Eimeria lineage (Apicomplexa: Eimeriidae). [PDF]
Groch KR +8 more
europepmc +1 more source
Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire +3 more
wiley +1 more source
Heat Shock Protein Inhibitor Tanespimycin (17AAG) Suppresses SARS-CoV-2 Main Protease Activity and Is More Potent Than Clinically Approved Antiviral Nirmatrelvir. [PDF]
Mukherjee G +4 more
europepmc +1 more source
Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin +6 more
wiley +1 more source
Illness perception and insomnia among patients with maintenance hemodialysis: a moderated mediation model of fear of progression and self-compassion. [PDF]
Huang Y +8 more
europepmc +1 more source
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen +4 more
wiley +1 more source
Phenolate-Rich Anionic Covalent Organic Frameworks with Engineered Reticular Microenvironments Enable Selective Dye Capture from Model Solutions and Real Textile Wastewater. [PDF]
Nozaki M +9 more
europepmc +1 more source

