Results 31 to 40 of about 284,181 (291)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Additional file 10: of The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p [PDF]

, 2016
List of miR-342-3p mimic-regulated genes in RAW264.7 mouse macrophages.
Cei Abreu-Goodger (10072), Zsolt Czimmerer (285768), Eva Varallyay (285776), Sudhir Tattikota (3576881), Laszlo Nagy (285790), Cesaré Vázquez (3576884), Zsolt Bacso (3576890), Gergely Nagy (1611460), Bence Daniel (3576893), Tamas Varga (1482442), Xin Yan (17064), Dominik Rückerl (528133), Judith Allen (3576896), Attila Horvath (285787), Zsuzsanna Nagy (64689), Matthew Poy (3576905), Quang Doan-Xuan (3576887), Mate Kiss (3576902), Szilard Poliska (3576899)   +18 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Homocysteine Is a Risk Factor in Predialysis Patients When Associated with Malnutrition and Inflammation

International Journal of Nephrology, 2010
The increased level of plasma total homocysteine (tHcy) in chronic kidney disease patients has been reported as a new and independent risk factor for cardiovascular disease.
Ana de Lurdes Agostinho Cabrita Vieira, Alexandre Baptista, Anabela Malho, Ana Pinho, Ana Paula Silva, Idalécio Bernardo, Pedro Leão Neves   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Enhancing Mungbean Productivity and Profitability through Zinc and Iron Application in Western Rajasthan

International Journal of Bio-Resource and Stress Management, 2020
A field experiment was conducted during kharif season (July to September), 2018 at Agricultural Research Station, Mandor, Agriculture University, Jodhpur (Rajasthan), India to examine the performance of mungbean with soil application and foliar spray of
Navratan Gahlot, Moola Ram, Hanuman Prasad Parewa, R. C. Meena, Sarita   +4 more
doaj  

Production of two charm quark–antiquark pairs in single-parton scattering within the kt-factorization approach

Physics Letters B, 2015
We present first results for the 2→4 single-parton scattering gg→cc¯cc¯ subprocess for the first time fully within the kt-factorization approach. In this calculation we have used the Kimber–Martin–Ryskin unintegrated gluon distribution which effectively ...
Andreas van Hameren, Rafał Maciuła, Antoni Szczurek   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Domain Structure and Magnetization Reversal Mechanism in Co/Pd Nanopatterned Multilayer

Proceedings, 2019
Fabrication and modeling of patterned thin films with perpendicular. [...]
Paweł Sobieszczyk, Michał Krupiński, Piotr Zieliński, Marta Marszałek   +3 more
doaj   +1 more source

Investigations of Muon Flux Variations Detected Using Veto Detectors of the Digital Gamma-rays Spectrometer

Applied Sciences, 2021
This paper presents the results of cosmic ray muons flux monitoring registered by a digital gamma-ray spectrometer’s active shield made of five large plastic scintillators.
Krzysztof Gorzkiewicz, Jerzy W. Mietelski, Zbigniew Ustrnul, Piotr Homola, Renata Kierepko, Ewa Nalichowska, Kamil Brudecki   +6 more
doaj   +1 more source