Results 1 to 10 of about 235,900 (237)

Emerging Role of miR-345 and Its Effective Delivery as a Potential Therapeutic Candidate in Pancreatic Cancer and Other Cancers

Pharmaceutics, 2021
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with high mortality, poor prognosis, and palliative treatments, due to the rapid upregulation of alternative compensatory pathways and desmoplastic reaction.
Nagabhishek Sirpu Natesh, Brianna M. White, Maia M. C. Bennett, Metin Uz, Rakhee Rathnam Kalari Kandy, Surinder K. Batra, Surya K. Mallapragada, Satyanarayana Rachagani   +7 more
doaj   +1 more source

Antifungal Activity of Isavuconazole and Comparator Agents against Contemporaneous Mucorales Isolates from USA, Europe, and Asia-Pacific

Journal of Fungi, 2023
Isavuconazole is the only US FDA-approved antifungal for treating invasive mucormycosis. We evaluated isavuconazole activity against a global collection of Mucorales isolates.
Cecilia G. Carvalhaes, Paul R. Rhomberg, Michael D. Huband, Michael A. Pfaller, Mariana Castanheira   +4 more
doaj   +1 more source

Anterior proliferative vitreoretinopathy in a patient with Coats disease [PDF]

International Journal of Ophthalmology, 2018
Letter to the ...
Satoru Kase, Shohei Mori, Kousuke Noda, Susumu Ishida   +3 more
doaj   +1 more source

Charles E. Curran, Sixty Years of Moral Theology: Readings in Moral Theology no. 20

Acta Universitatis Carolinae Theologica, 2021
Book review on Charles E. Curran, Sixty Years of Moral Theology: Readings in Moral Theology no. 20, New York: Paulist Press, 2020, 255 s., ISBN 978-0-8091-0665-3.
Ondřej Havelka
doaj   +1 more source

„A to se vyplatí!“ Morálka jako spolupráce?

Reflexe, 2021
The article is a polemics with those conceptions of the nature of morality which, based on an inquiry into the evolutionary origins of morality, locate its meaning in a society’s cooperation (backed by rules) for the purpose of joint success.
Ondřej Beran
doaj   +1 more source

Smrt a čas. Poslední přednášky Emmanuela Levinase

Reflexe, 2021
Reflection on the last lectures of Emmanuel Levinas.
Ondřej Kvapil
doaj   +1 more source

Relative Entropy in Determining Degressive Proportional Allocations

Entropy, 2021
The principle of degressively proportional apportionment of goods, being a compromise between equality and proportionality, facilitates the application of many different allocation rules.
Katarzyna Cegiełka, Piotr Dniestrzański, Janusz Łyko, Arkadiusz Maciuk, Maciej Szczeciński   +4 more
doaj   +1 more source

A case of giant cell arteritis presenting with nodular posterior scleritis mimicking a choroidal mass

American Journal of Ophthalmology Case Reports, 2020
Purpose: Herein we present a case of giant cell arteritis presenting with nodular posterior scleritis and exudative retinal detachment mimicking a choroidal mass.
Caroline Awh, David A. Reichstein, Akshay S. Thomas   +2 more
doaj   +1 more source

Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis in polycystic liver disease

JHEP Reports, 2021
Background & Aims: Polycystic liver disease (PLD) is characterised by increased autophagy and reduced miRNA levels in cholangiocytes. Given that autophagy has been implicated in miRNA regulation, we tested the hypothesis that increased autophagy ...
Tatyana Masyuk, Anatoliy Masyuk, Christy Trussoni, Brynn Howard, Jingyi Ding, Bing Huang, Nicholas LaRusso   +6 more
doaj   +1 more source

Do Medical Universities Students Use Cognitive Enhancers while Learning?—Conclusions from the Study in Poland

Life, 2023
Background: Stress and everyday problems may impact memory and cognition. Therefore, many people use cognitive enhancers (CEs), sold for prescription, as over-the-counter drugs, or dietary supplements, believing they may help with everyday functioning ...
Anna Merwid-Ląd, Michał Passon, Paweł Drymluch, Maciej Głuszyński, Adam Szeląg, Agnieszka Matuszewska   +5 more
doaj   +1 more source