Results 161 to 170 of about 235,900 (237)

Projecting the benefit of vericiguat in PARADIGM‐HF and DAPA‐HF populations: Insights from the VICTORIA trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1479-1484, April 2025.
Abstract Aims The VICTORIA trial demonstrated a significant reduction in the primary composite outcome of heart failure (HF) hospitalization or cardiovascular death with vericiguat relative to placebo in high‐risk HF. This study aimed to contextualize treatment effects of vericiguat in populations with varying risk profiles simulated from the PARADIGM ...
Veraprapas Kittipibul   +13 more
wiley   +1 more source

Epidemiology of hospitalized heart failure in France based on national data over 10 years, 2012–2022

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1283-1294, April 2025.
Abstract Aims We aim to describe the incidence of HF hospitalization in France in the post‐pandemic era, the prevalence of HF cases and patients' characteristics, management and outcomes while focusing on sex, age and socio‐economic differences and to analyse time‐trends between 2012 and 2022.
Valérie Olié   +5 more
wiley   +1 more source

Metal‐Directed Self‐Assembly in a Beta‐Sheet Miniprotein Scaffold

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
A rationally engineered miniprotein, V14C, which is based on the beta β‐sheet Foldon domain, self‐assembles via a metal‐binding site to form well‐defined oligomers in the presence of Zn2+, Hg2+, and Cd2+. This modular design expands the toolbox for creating custom metalloproteins, enabling studies of metal–protein interactions for biochemical functions
Chandan Muni Reddy   +3 more
wiley   +1 more source

Mixed methods evaluation of a clinical decision support system to reduce variation in healthcare. [PDF]

open access: yesNPJ Digit Med
Pak A   +5 more
europepmc   +1 more source

T‐Shaped 8‐Aryl(ethynyl)‐Substituted Psoralens With Tunable Charge‐Transfer Absorption

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Starting from 8‐methoxypsoralen, new 8‐arylated and 8‐alkynylated psoralen derivatives are accessible by cross‐coupling. These T‐shaped π‐expanded chromophores are luminescent and photophysics reveal a highly polar excited state with tunable charge‐transfer character.
Lena T. Leusch, Thomas J. J. Müller
wiley   +1 more source

Appraising Policies Through Social Multi‐Criteria Evaluation: Lessons From a Systematic Review of Applications

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT In response to renewed interest in analytical tools that address complex policy problems and move beyond linear‐rational approaches in policy appraisal, Social Multi‐Criteria Evaluation (SMCE) integrates participatory approaches with multi‐criteria analysis (MCA), thereby incorporating specialised knowledge and diverse social values and ...
Egle Basyte Ferrari
wiley   +1 more source

Teacher‐Led Universal Eating Disorder Prevention Programmes in Schools: A Scoping Review

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective This scoping review seeks to evaluate the efficacy of teacher‐led interventions in mitigating risk factors related to eating disorders, considering the necessity for universal prevention programmes that can be effectively administered by educators.
Jessica Parker   +3 more
wiley   +1 more source

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