Results 1 to 10 of about 240,495 (213)

Total flavonoids of Abelmoschus manihot (L.) medic attenuate early renal injury in diabetic kidney disease by modulating the LINC00665/miR-379-5p axis [PDF]

open access: yesPharmaceutical Biology
‌Context:‌ Huangkui capsule (HKC), derived from Abelmoschus manihot (L.) Medic, is clinically utilized for diabetic kidney disease (DKD) treatment. Its primary bioactive components are the total flavonoids of A. manihot (L.) (TFA).
Nan Li   +5 more
doaj   +2 more sources

MiR-379-5p aggravates experimental autoimmune uveitis in mice via the regulation of SEMA3A

open access: yesAutoimmunity, 2021
Uveitis is a disease resulting in the inflammation of uveal tracts, but the factors resulting in uveitis is still obscure. Previous studies have shown that miR-379-5p was involved in the pathogenesis of several diseases, however, the role and regulatory ...
Zhengxuan Jiang
exaly   +2 more sources

MicroRNA‐379 inhibits laryngeal carcinoma cell proliferation and invasion through directly targeting TCF‐4

open access: yesKaohsiung Journal of Medical Sciences, 2019
The expression pattern, functions, and detailed regulatory mechanisms of miR‐379 in laryngeal carcinoma remain unknown. In the present study, we aimed to uncover novel potential miR‐379 targets and shed light on its roles in laryngeal carcinoma.
Jin-Long Wei
exaly   +2 more sources

MicroRNA‐379‐5p targets MAP3K2 to reduce autophagy and alleviate neuronal injury following cerebral ischemia via the JNK/c‐Jun signaling pathway

open access: yesKaohsiung Journal of Medical Sciences, 2022
MicroRNAs (miRNAs) are abundant in neurons and play key roles in the function and development of the nervous system. This study focuses on the function of miR‐379‐5p in neurological function recovery during ischemic stroke.
Kang-Yong Liu
exaly   +2 more sources

MicroRNA-379-5p regulates free cholesterol accumulation and relieves diet induced-liver damage in db/db mice via STAT1/HMGCS1 axis

open access: yesMolecular Biomedicine, 2022
Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driving factors in the transition from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).
Ningning Ma, Xiao-Ding Xu, Gong Likun
exaly   +2 more sources

miR-379-5p retards the proliferation and differentiation of goat skeletal muscle satellite cells by targeting LIN28B [PDF]

open access: yesFrontiers in Veterinary Science
MicroRNAs (miRNAs) are emerging as crucial regulators of skeletal muscle development and regeneration; however, the biological functions of many miRNAs remain to be elucidated.
Wenyue Hou   +8 more
doaj   +2 more sources

Characterization of the Aerobic Anoxygenic Phototrophic Bacterium Sphingomonas sp. AAP5

open access: yesMicroorganisms, 2021
An aerobic, yellow-pigmented, bacteriochlorophyll a-producing strain, designated AAP5 (=DSM 111157=CCUG 74776), was isolated from the alpine lake Gossenköllesee located in the Tyrolean Alps, Austria.
Karel Kopejtka   +7 more
doaj   +1 more source

Gradual Response of Cyanobacterial Thylakoids to Acute High-Light Stress—Importance of Carotenoid Accumulation

open access: yesCells, 2021
Light plays an essential role in photosynthesis; however, its excess can cause damage to cellular components. Photosynthetic organisms thus developed a set of photoprotective mechanisms (e.g., non-photochemical quenching, photoinhibition) that can be ...
Myriam Canonico   +4 more
doaj   +1 more source

Phylum Gemmatimonadota and Its Role in the Environment

open access: yesMicroorganisms, 2022
Bacteria are an important part of every ecosystem that they inhabit on Earth. Environmental microbiologists usually focus on a few dominant bacterial groups, neglecting less abundant ones, which collectively make up most of the microbial diversity.
Izabela Mujakić   +2 more
doaj   +1 more source

Microdomains heterogeneity in the thylakoid membrane proteins visualized by super-resolution microscopy

open access: yesPhotosynthetica, 2023
The investigation of spatial heterogeneity within the thylakoid membrane (TM) proteins has gained increasing attention in photosynthetic research. The recent advances in live-cell imaging have allowed the identification of heterogeneous organisation of ...
R. KAŇA, B. ŠEDIVÁ, O. PRÁŠIL
doaj   +1 more source

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