Results 1 to 10 of about 2,145,731 (206)

MiR-379-5p aggravates experimental autoimmune uveitis in mice via the regulation of SEMA3A

open access: yesAutoimmunity, 2021
Uveitis is a disease resulting in the inflammation of uveal tracts, but the factors resulting in uveitis is still obscure. Previous studies have shown that miR-379-5p was involved in the pathogenesis of several diseases, however, the role and regulatory ...
Mohan Li   +4 more
exaly   +2 more sources

MicroRNA‐379‐5p targets MAP3K2 to reduce autophagy and alleviate neuronal injury following cerebral ischemia via the JNK/c‐Jun signaling pathway

open access: yesKaohsiung Journal of Medical Sciences, 2022
MicroRNAs (miRNAs) are abundant in neurons and play key roles in the function and development of the nervous system. This study focuses on the function of miR‐379‐5p in neurological function recovery during ischemic stroke.
Kang-Yong Liu
exaly   +2 more sources

MicroRNA-379-5p regulates free cholesterol accumulation and relieves diet induced-liver damage in db/db mice via STAT1/HMGCS1 axis

open access: yesMolecular Biomedicine, 2022
Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driving factors in the transition from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).
Yunxia Dong   +8 more
exaly   +2 more sources

Characterization of the Aerobic Anoxygenic Phototrophic Bacterium Sphingomonas sp. AAP5

open access: yesMicroorganisms, 2021
An aerobic, yellow-pigmented, bacteriochlorophyll a-producing strain, designated AAP5 (=DSM 111157=CCUG 74776), was isolated from the alpine lake Gossenköllesee located in the Tyrolean Alps, Austria.
Karel Kopejtka   +7 more
doaj   +1 more source

Gradual Response of Cyanobacterial Thylakoids to Acute High-Light Stress—Importance of Carotenoid Accumulation

open access: yesCells, 2021
Light plays an essential role in photosynthesis; however, its excess can cause damage to cellular components. Photosynthetic organisms thus developed a set of photoprotective mechanisms (e.g., non-photochemical quenching, photoinhibition) that can be ...
Myriam Canonico   +4 more
doaj   +1 more source

Phylum Gemmatimonadota and Its Role in the Environment

open access: yesMicroorganisms, 2022
Bacteria are an important part of every ecosystem that they inhabit on Earth. Environmental microbiologists usually focus on a few dominant bacterial groups, neglecting less abundant ones, which collectively make up most of the microbial diversity.
Izabela Mujakić   +2 more
doaj   +1 more source

Microdomains heterogeneity in the thylakoid membrane proteins visualized by super-resolution microscopy

open access: yesPhotosynthetica, 2023
The investigation of spatial heterogeneity within the thylakoid membrane (TM) proteins has gained increasing attention in photosynthetic research. The recent advances in live-cell imaging have allowed the identification of heterogeneous organisation of ...
R. KAŇA, B. ŠEDIVÁ, O. PRÁŠIL
doaj   +1 more source

Exploring Mycosporine-Like Amino Acids (MAAs) as Safe and Natural Protective Agents against UV-Induced Skin Damage

open access: yesAntioxidants, 2021
Prolonged exposure to harmful ultraviolet radiation (UVR) can induce many chronic or acute skin disorders in humans. To protect themselves, many people have started to apply cosmetic products containing UV-screening chemicals alone or together with ...
Anjali Singh   +3 more
doaj   +1 more source

miR-379 mediates insulin resistance and obesity through impaired angiogenesis and adipogenesis regulated by ER stress

open access: yesMolecular Therapy: Nucleic Acids, 2022
We investigated the role of microRNA (miR-379) in the pathogenesis of obesity, adipose tissue dysfunction, and insulin resistance (IR). We used miR-379 knockout (miR-379KO) mice to test whether loss of miR-379 affects high-fat diet (HFD)-induced obesity ...
Maryam Abdollahi   +9 more
doaj   +1 more source

Food Systems and Food Security: The Role of Small Farms and Small Food Businesses in Santiago Island, Cabo Verde

open access: yesAgriculture, 2020
This study aims to analyse the role and contribution of small farms and small food businesses on the food system and food security. Drawing on a conceptual framework, methodology, and data from the EU H2020 ‘SALSA-Small farms, small food businesses and ...
Arlindo Rodrigues Fortes   +5 more
doaj   +1 more source

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