Results 151 to 160 of about 2,158,309 (327)

Impact of secured prescription implementation on ambulatory pregabalin use in France: A regional assessment in the French Nouvelle‐Aquitaine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The French authorities mandated the use of secure prescriptions for pregabalin on May 2021. This study aimed to evaluate the impact of this measure on pregabalin use and misuse in Nouvelle‐Aquitaine, a southwestern French region with around six million inhabitants.
Maika Munech‐Herran, Véronique Moysan, Bruno Lescarret, Clément Mathieu, Antoine Pariente, Nicolas Rousselot   +5 more
wiley   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi, Shotaro Aso, So Sato, Hideo Yasunaga   +3 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Hydrological Interpretation of Basin Morphology [PDF]

, 1978
Completion Report OWRT Agreement No. 14-31-0001-5002 OWRT Project A-049-ALASHydrologic processes in a particular basin are governed by three groups of factors: input regimes of mass and energy, the nature of mass and energy transfer and ...
Fox, John D.
core  

On Second Thought: The Impact of Confessions, DNA, and Belief Perseverance on Students' Perceptions of Guilt and Interrogations

Behavioral Sciences &the Law, EarlyView.
ABSTRACT Despite growing public knowledge of false confession cases, research with students and community members continues to find that people assume confessions indicate guilt. The present research explored the implications of belief perseverance: the tendency to maintain a belief even when confronted with compelling contradictory evidence.
Taya D. Henry, Kimberley A. Clow, Victoria Hall   +2 more
wiley   +1 more source

Toward behavioural innovation economics – Heuristics and biases in choice under novelty [PDF]

A framework for ‘behavioural innovation economics’ is proposed here as a synthesis of behavioural economics and innovation economics in the specific context of choice under novelty.
Jason Potts, Kate Morrison
core  

MicroRNA-379-5p attenuates cancer stem cells and reduces cisplatin resistance in ovarian cancer by regulating RAD18/Polη axis

Cell Death and Disease
Ovarian cancer (OC) is an aggressive malignancy of the female reproductive organs, associated with a low 5-year survival rate. Emerging evidence suggests the pivotal role of microRNAs (miRNAs) in regulating chemoresistance and metastasis in OC, primarily
Devendra Shukla, Sanjay Mishra, Tanima Mandal, Manish Charan, Ajeet Kumar Verma, Md Maqsood Ahamad Khan, Nabanita Chatterjee, Amit Kumar Dixit, Senthil Kumar Ganesan, Ramesh K. Ganju, Amit Kumar Srivastava   +10 more
doaj   +1 more source

Chain Versus Ring: Characterization of a Meta‐Phenylene Ladder Polymer and Its Octameric Macrocycle

Chemistry – A European Journal, EarlyView.
The synthesis and comprehensive spectral and photophysical analysis of a methyl‐substituted ladder meta‐phenylene macrocycle (MeLMMP) and its polymer analogue (MeLPMP) show that, despite differing topologies (macrocycle vs. polymer), both display nearly identical electronic and photophysical properties due to cross‐conjugation.
Paulo D. Nunes Barradas, Hauke J. Jötten, Ngoc B. B. Nguyen, Ullrich Scherf, J. Sérgio de Seixas de Melo   +4 more
wiley   +1 more source

Asymptotic properties of cross‐classified sampling designs

Canadian Journal of Statistics, EarlyView.
Abstract We investigate the family of cross‐classified sampling designs across an arbitrary number of dimensions. We introduce a variance decomposition that enables the derivation of general asymptotic properties for these designs and the development of straightforward and asymptotically unbiased variance estimators.
Jean Rubin, Guillaume Chauvet
wiley   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source