Macrophages and Galectin 3 Control Bacterial Burden in Acute and Subacute Murine Leptospirosis That Determines Chronic Kidney Fibrosis [PDF]
, 2018 Previous studies have suggested that macrophages may contribute to acute Leptospira dissemination, as well as having a major role in kidney fibrosis. Our aim was to characterize the role of macrophages and galectin 3 (Gal-3) on the survival, clinical ...
Carrera Silva, Eugenio Antonio +10 more
core +3 more sources
Development of an Antioxidant Phytoextract of Lantana grisebachii with Lymphoprotective Activity against In Vitro Arsenic Toxicity [PDF]
, 2014 Phytochemicals have been presumed to possess prophylactic and curative properties in several pathologies, such as arsenic- (As-induced immunosuppression. Our aim was to discover a lymphoprotective extract from Lantana grisebachii Stuck. (Verbenaceae)(LG).
Albrecht, Claudia +5 more
core +4 more sources
Estradiol activates PI3K/Akt/GSK3 pathway under chronic neurodegenerative conditions triggered by perinatal asphyxia [PDF]
, 2018 Perinatal asphyxia (PA) remains as one of the most important causes of short-term mortality, psychiatric and neurological disorders in children, without an effective treatment.
Bellini, Maria Jose +3 more
core +2 more sources
Immunization with antigenic extracts of Leishmania associated with Montanide ISA 763 adjuvant induces partial protection in BALB/c mice against Leishmania (Leishmania) amazonensis infection [PDF]
, 2014 Background/Purpose: A proper adjuvant has a relevant role in vaccine formulations to generate an effective immune response. In this study, total Leishmania antigen (TLA) formulated with Montanide ISA 763 or R848 as adjuvants were evaluated as a first ...
Cargnelutti, Diego Esteban +6 more
core +1 more source
CMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects [PDF]
, 2020 Parkinson's disease (PD) is a neurodegenerative disorder for which only symptomatic treatments are available. Repurposing drugs that target α-synuclein aggregation, considered one of the main drivers of PD progression, could accelerate the development of
Avila, Cesar Luis +10 more
core +1 more source
The ERα membrane pool modulates the proliferation of pituitary tumours [PDF]
, 2019 The molecular mechanisms underlying the ERα nuclear/cytoplasmic pool that modulates pituitary cell proliferation have been widely described, but it is still not clear how ERα is targeted to the plasma membrane.
Chumpen Ramirez, Sabrina Vanesa +9 more
core +1 more source
Effects of dietary omega-3 PUFAs on growth and development: Somatic, neurobiological and reproductive functions in a murine model [PDF]
, 2018 Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) are relevant to fetal and infant growth and development. Objective: to assess whether long-term exposure to dietary ω-3 PUFA imbalance alters pre- and/or postnatal pups' development and reproductive ...
Bianconi, Santiago +8 more
core +2 more sources
Anales de Pediatría (English Edition), 2021 Introduction: Diet and physical activity are factors that have key roles in childhood overweight and obesity prevention. Appropriate assessment of these factors is an essential task in public health.
María del Mar Fernández-Álvarez +5 more
doaj +1 more source
Mitochondrial dysfunction in skeletal muscle during experimental Chagas disease [PDF]
, 2015 Trypanosoma cruzi invasion and replication in cardiomyocytes and other tissues induce cellular injuries and cytotoxic reactions, with the production of inflammatory cytokines and nitric oxide, both sources of reactive oxygen species. The myocyte response
Bazán, Paola Carolina +8 more
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Enrique Pedro Aznares. Primer profesor de Historia de la Medicina en Córdoba
Revista de Salud Pública, 2014 La Historia es una de las disciplinas puestas al servicio de la Medicina y otras Ciencias de la Salud. Desde comienzos de los tiempos y hasta la actualidad y por sus características evolutivas y sus valores informativos y formativos, la Historia permite
Norma Acerbi Cremades
doaj +1 more source