Results 41 to 50 of about 77,255,410 (183)

Decellularised Corneal Stromal Lamina With or Without Autologous Adipose‐Derived Adult Stem Cells for Advanced Keratoconus: 1‐Year Results of a Phase I/IIa Clinical Trial

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang, Jorge L. Alió del Barrio, Alejandra E. Rodriguez, Rafael I. Barraquer, Francisco Arnalich‐Montiel, David Mingo‐Botín, María Eugenia Fernández Santos, Jorge L. Alió   +7 more
wiley   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

The FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz, Daniel Pérez‐Calixto, Jorge Carretero‐Ortega, Aida Gabriela Guzman‐López, Diana Cristina Pinto‐Dueñas, Mariana Hernández‐Juárez, Alejandra Jiménez‐Escobar, Adriana Rodríguez‐Hernández, Beatriz Díaz‐Bello, Nathalia Serna‐Márquez, Miguel Ángel Peña‐Rico, Laura Gómez‐Romero, Francisco Gabriel Vázquez‐Cuevas, Genaro Vázquez‐Victorio   +13 more
wiley   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Transcranial electric stimulation in chronic pain: Effects on quality of life, physical function, activity and clinical status

Journal of Neuropsychology, EarlyView.
Abstract Transcranial electric stimulation represents a promising non‐invasive neuromodulatory technique targeting maladaptive nociplastic changes in chronic pain (CP) with analgesic effects. However, its impact beyond pain reduction on broader outcomes such as quality of life (QoL) and physical function remains unclear.
Antonio Gil‐Ugidos, María López‐Corchón, Gavriella Τsiarleston, Víctor Segura‐Jiménez, María Teresa Carrillo‐de‐la‐Peña   +4 more
wiley   +1 more source

Tecnología, Calidad de Atención y Costos de las Actividades Medicas

Medicina, 1987
<p><strong>Enfoque por Síndromes</strong></p><p><strong>Evolución</strong><br />El concepto de Salud-Enfermedad para nuestras comunidades ha variado fundamentalmente a través del tiempo, a pesar de que ...
Ricardo Galán Morera
doaj  

Tick‐borne diseases in subtropical dairy farming: The role of calf rearing strategies in antibody and antigen prevalence Enfermedades Transmitidas por Garrapatas en la Ganadería Lechera subtropical: El Papel de las Estrategias de Crianza de Terneros en la Prevalencia de Anticuerpos y Antígenos

Medical and Veterinary Entomology, EarlyView.
Tropical farmers try to adapt calf‐rearing systems to temperate dairy industry standards. Calves in tick‐infested areas develop stronger immunity to TBD under controlled exposure to ticks. Early tick exposure promotes sustainable management, balancing tick infestation and developing TBD immunity.
Daniela Balseca, Valeria Paucar‐Quishpe, Richar Rodríguez‐Hidalgo, Ximena Pérez‐Otáñez, Darío Cepeda‐Bastidas, Cecilia Pérez‐Escalante, María‐Augusta Chávez‐Larrea, Sandra Enríquez, Jorge Grijalva, Sophie O. Vanwambeke, Claude Saegerman, Lenin Ron‐Garrido   +11 more
wiley   +1 more source

Levodopa and Melanoma: Practical Recommendations for Parkinson's Disease—International Parkinson and Movement Disorder Society Scientific Issues Committee Viewpoint

Movement Disorders Clinical Practice, EarlyView.
Giorgia Sciacca, Inas Elsayed, Santiago Perez‐Lloret, Tiago F. Outeiro, Vivek K. Unni, Jeffery H. Kordower, Daniela Berg, Lorraine V. Kalia, on behalf of the MDS Scientific Issues Committee, Jane Alty, Alexander Balck, Daniela Berg, Per Borghammer, Inas Elsayed, Yue Huang, Walaa Kamel Elsayed, Jeffrey Kordower, Alexander Lehn, Michele Matarazzo, Tiago Mestre, Tiago Outeiro, Gian Pal, Santiago Perez Lloret, Roopa Rajan, Sephira Ryman, Giorgia Sciacca, Per Svenningsson, Lorraine Kalia   +27 more
wiley   +1 more source

Ecological and Individual‐Level Factors Associated With Hantavirus Cardiopulmonary Syndrome Notifications and in‐Hospital Mortality Among Hospitalized Patients in Chile, 2005–2022

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Hantavirus cardiopulmonary syndrome (HCPS) is a severe zoonotic disease caused by Orthohantavirus andesense (Andes virus, ANDV), with significant public health burden in Chile. Despite decades of surveillance, knowledge gaps remain regarding the ecological drivers of notification burden and the individual‐level determinants of in ...
Benjamín Diethelm‐Varela, Nicolhole Atero, Fernanda Sánchez‐Rodríguez, Constanza Martínez‐Valdebenito, Carolina Henríquez, Francisca Córdova‐Bührle, Marcela Ferrés, Fernando O. Mardones   +7 more
wiley   +1 more source

Galectin‐3 plasma levels are associated with left atrial contractile function in long‐distance runners

Experimental Physiology, EarlyView.
Abstract High‐intensity endurance exercise induces myocardial remodelling as an adaptive response to sustained volume overload, but excessive cumulative training might also favour deleterious cardiac remodelling, including atrial fibrosis. Whether acute marathon running engages circulating fibrosis‐related biomarkers and whether these biomarkers track ...
Felipe Contreras‐Briceño, Fernanda Sanhueza‐Olivares, Rodrigo Fernández, Silvana Llevaneras, Pablo F. Castro, Luigi Gabrielli, Mario Chiong   +6 more
wiley   +1 more source

VII Congreso de especialidades clínicas y ciencias básicas. La salud hacia el siglo XXI

, 1995
Encuentro de egresados / VII  Congreso de Especialidades Clinicas y Ciencias Básicas. La Salud Hacia el Siglo XXI  / Concurso Nacional de Trabajos de Investigación para residentes y estudiantes de medicina / Concurso de ...
Revista, Facultad de Medicina
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