Results 51 to 60 of about 2,403,682 (282)

Brain Tissue Low-Level Mosaicism for MTOR Mutation Causes Smith–Kingsmore Phenotype with Recurrent Hypoglycemia—A Novel Phenotype and a Further Proof for Testing of an Affected Tissue

Diagnostics, 2021
De novo somatic variants in genes encoding components of the PI3K–AKT3–mTOR pathway, including MTOR, have been linked to hemimegalencephaly or focal cortical dysplasia.
Krzysztof Szczałuba, Małgorzata Rydzanicz, Anna Walczak, Joanna Kosińska, Agnieszka Koppolu, Anna Biernacka, Katarzyna Iwanicka-Pronicka, Wiesława Grajkowska, Elżbieta Jurkiewicz, Paweł Kowalczyk, Rafał Płoski   +10 more
doaj   +1 more source

Molecular Gas in the Powerful Radio Galaxies 3C~31 and 3C~264: Major or Minor Mergers?

, 2000
We report the detection of $^{12}$CO~($1 \to 0$) and $^{12}$CO~($2 \to 1$) emission from the central regions ($\lesssim 5$--$10 {\rm kpc}$) of the two powerful radio galaxies 3C~31 and 3C~264.
Dinh-V-Trung, , Françoise Combes, Gordon M. A., Jeremy Lim, Stephane Leon, Wiklind T.   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Anisotropic Wetting Behavior on Gradient Surface Structures Fabricated by Direct Laser Interference Patterning on Stainless Steel

Advanced Materials Interfaces
In this work, anisotropic line‐like textures with gradually increasing spatial periods from 2.0 to 4.8 µm are fabricated on stainless steel by two‐beam Direct Laser Interference Patterning using a ps‐laser source.
Tianhao Wu, Marcos Soldera, Bogdan Voisiat, Ignacio Tabares, Andrés Fabián Lasagni   +4 more
doaj   +1 more source

Loop-Mediated Isothermal Amplification (LAMP): The Better Sibling of PCR?

Cells, 2021
In 1998, when the PCR technique was already popular, a Japanese company called Eiken Chemical Co., Ltd. designed a method known as the loop-mediated isothermal amplification of DNA (LAMP).
Marianna Soroka, Barbara Wasowicz, Anna Rymaszewska   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Determining the spring biomass peak of the smallest plankters in selected vendace lakes in Western Pomerania

Archives of Polish Fisheries, 2014
The aim of this study was to determine the prevalence peak of the smallest plankters that are an adequate food resource for vendace (Coregonus albula L.) larvae.
Domagała Józef, Ługocki Słukasz, Czerniawski Robert, Pilecka-Rapacz Małgorzata   +3 more
doaj   +1 more source

Identification of γ-ray emission from 3C 345 and NRAO 512 [PDF]

, 2011
For more than 15 years, since the days of the Energetic Gamma-Ray Experiment Telescope (EGRET) on board the Compton Gamma-Ray Observatory (CGRO; 1991−2000), it has remained an open question why the prominent blazar 3C 345 was not reliably detected at γ ...
Max-Moerbeck, W., Schinzel, F. K.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Non-Equilibrium Modeling of the Fe XVII 3C/3D ratio for an Intense X-ray Free Electron Laser

, 2017
We present a review of two methods used to model recent LCLS experimental results for the 3C/3D line intensity ratio of Fe XVII (Bernitt et al. 2012), the time-dependent collisional-radiative method and the density-matrix approach.
Ballance, C. P., Fogle, M., Fontes, C. J., Li, Y., Loch, S. D.   +4 more
core   +1 more source