Results 221 to 230 of about 29,330 (299)

QSProteome: a community-driven interactive platform for large-scale exploration and evaluation of predicted protein complex structures. [PDF]

Nucleic Acids Res
Catoiu EA, Kambo D, Rodriguez B, Vear K, Wang Z, Akpata J, Shah J, Ayoub R, Hofmann M, Ananda K, Tantry A, Gupta I, Anwyl R, Faucher C, Nichols J, Ton B, Marchal LO, Palsson BO.   +17 more
europepmc   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Game Elements in Military Trauma Care Education: Systematic Review. [PDF]

JMIR Serious Games
Stathakarou N, Kononowicz AA, Harjani MG, Swain C, Karlgren K.   +4 more
europepmc   +1 more source

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source

Impact of the Practice of Playing Video Games on Technical Skills Development in Preclinical Dental Education: Preliminary Cross-Sectional Observational Study. [PDF]

JMIR Form Res
Clouet R, Remaud T, Boeffard C, Serisier S, Gaudin A, Prud'homme T.   +5 more
europepmc   +1 more source

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

Risk Factors and Coinfection Dynamics of Pathogens in Wild Turkeys (<i>Meleagris gallopavo</i>) From Pennsylvania, USA. [PDF]

Ecol Evol
Koch RW, Hoarau AOG, de Ruyter T, Duffy C, Pascarosa L, Campbell KA, Maynard CL, Cushman A, Flick H, Musselman A, Patsko J, Bealer R, Rhone G, Casalena MJ, Di Salvo A, Duren K, Armstrong JT, Buderman FE, Larsen RS, Sobotyk C, Miller EA, Niedringhaus KD, Geary B, Anis E, Gagne RB.   +24 more
europepmc   +1 more source

Injectable Hydrogel with Rapid Coagulation, Low Swelling, and High Burst Pressure Tolerance Properties for Long‐Term Management of Bleeding Wound

Advanced Science, EarlyView.
An injectable PACmC hydrogel with “rigid island‐flexible chain” architecture is developed, featuring low swelling (49.2% within 7 d), strong wet adhesion (46.5 kPa), and high burst pressure (701 mm Hg), which can achieve rapid hemostasis and long‐term sealing in rabbit and porcine models of hepatic and splenic hemorrhage.
Yang Ouyang, Wenfeng Qiu, Weiwen Liang, Xin Zhang, Weijie Liu, Zixin Chen, Yifei Li, Hui Wang, Youchen Tang, Min Li, Rongkang Huang, Zijian Chen, Binghua Ma   +12 more
wiley   +1 more source

On-Field Assessment of Joint Load in Football Using Machine Learning (Part II). [PDF]

Sensors (Basel)
Benjaminse A, Mendicino M, Nijmeijer EM, Margheriti P, Gokeler A, Di Paolo S.   +5 more
europepmc   +1 more source