Results 31 to 40 of about 179,536 (231)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A Novel Analog Interface Using 3D Printed Electrodes for Mixed Voltage-Current Mode EEG

IEEE Access
This work presents a comprehensive study on a novel analog interface for single- and dual-channel electroencephalographic (EEG) analysis, employing current-mode active building blocks (ABBs), specifically the second-generation current conveyor (CCII) and
Andrea Rotondo, Gianluca Barile, Giuseppe Ferri, Vincenzo Stornelli   +3 more
doaj   +1 more source

Hydrocarbon Accumulation Analysis Based on Quasi-3D Seismic Data in the Turbulent Area of the Northern South China Sea

Journal of Marine Science and Engineering, 2023
The Mesozoic strata in the northern South China Sea have good potential for oil and gas exploration. The Dongsha Waters, where the study area is located, have complex seismic and geological characteristics; in particular, turbulence is very prominent in ...
Zhongquan Zhao, Guangjian Zhong, Ming Sun, Changmao Feng, Guanghong Tu, Hai Yi   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Failure Behaviour of Jointed Rock Masses with 3D Nonpenetrating Joints under Uniaxial Compression: Insights from Discrete Element Method Modelling

Applied Sciences, 2022
It is well known that joints or fissures have an important effect on the failure mechanism of natural rocks. Previously, many numerical and experimental papers have been carried out to study the strength anisotropy and failure characteristics of jointed ...
Rihong Cao, Hua Dai, Rubing Yao, Hang Lin, Kaihui Li   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Teleoperated Service Robot with an Immersive Mixed Reality Interface

Информатика и автоматизация, 2021
Teleoperated service robots can perform more complex and precise tasks as they combine robot skills and human expertise. Communication between the operator and the robot is essential for remote operation and strongly affects system efficiency.
Angelica Nakayama, Daniel Ruelas, Jesus Savage, Ernesto Bribiesca   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source