[Video] Scientists turn to 3D technology to help restore Notre Dame [PDF]
, 2021 "Scientists have enlisted the help of 3D imaging technology to restore Notre Dame to its former glory. A digital team from France's National Centre for Scientific Research has been working on the site for the past two years since the cathedral was ...
Consortium 3D SHS Team
core
Réaliser un projet de modèles numériques 3D pour le patrimoine. Guide de rédaction d'un cahier des charges [PDF]
, 2020 "Dans le cadre des activités du Consortium 3D de la TGIR Huma-Num, de nombreuses rencontres ont eu lieu réunissant des spécialistes aux profils divers (historiens, archéologues, informaticiens, architectes, ingénieurs 3D, archivistes …etc.) afin de ...
Consortium 3D SHS Team
core
Molecular modelling studies on adamantane-based Ebola virus GP-1 inhibitors using docking, pharmacophore and 3D-QSAR [PDF]
, 2019 The pathogenic Ebola virus (EBOV) causes a potential health risk and global spread. To date, few drugs are available for the treatment of Ebola virus disease (EVD) that allow researchers to use computational methods for designing potential drugs.
H.K. Chaudhari (6385988) +1 more
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3D-QSAR-based pharmacophore modelling of quinazoline derivatives for the identification of acetylcholinesterase inhibitors through virtual screening, molecular docking, molecular dynamics and DFT studies [PDF]
Alzheimer’s disease (AD) is a progressive neurological disorder responsible for the cognitive dysfunction and cognitive impairment in the patients. Acetylcholinesterase inhibitors (AChEIs) are used to treat AD however, these only provided symptomatic ...
Vijay Kumar (377076) +4 more
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Share - Publish - Store - Preserve. Methodologies, Tools and Challenges for 3D Use in Social Sciences and Humanities [PDF]
, 2020 "Through this White Paper, which gathers contributions from experts of 3D data as well as professionals concerned with the interoperability and sustainability of 3D research data, the PARTHENOS project aims at highlighting some of the current issues they
Consortium 3D SHS Team
core
Nonequivalent Effects of Diverse LogP Algorithms in Three QSAR Studies [PDF]
, 2015 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Despite of the availability and facility of accessing several algorithms for calculation of LogP in QSA(P)R studies, articles typically do not describe the selection procedure for the method ...
de Melo, EB, Ferreira, MMC
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A Review of 3D-QSAR in Drug Design [PDF]
Journal of the Chosun Natural Science, 2012 Quantitative structure-activity relationship (QSAR) methodologies have been applied for many years, to correlate the relationship between physicochemical properties of chemical substances and their biological activities to generate a statistical model for prediction of the activities of new chemical entities.
openaire +1 more source
Journal of Chemistry, 2013 The development of new therapies to treat hypertension and cardiovascular diseases. A series of 2,4,5-trisubstituted triazolinones aryl and nonaryl derivatives were subjected to Group-based QSAR, k-nearest neighbour molecular field analysis, and ...
Mukesh C. Sharma +2 more
doaj +1 more source
QSAR of Clerodane Diterpenoids with Cytotoxic and Antitumoral Activity Against V-79 Cells [PDF]
, 2015 This work deals with diterpenoids of the clerodane type, compounds isolated from the extracts of different plant organs from trees mainly of the Flacourtiaceae family.
Takahata, Y, Cramer, B
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Journal of Saudi Chemical Society, 2015 Context: In recent years phosphodiesterase V acts as an attractive target for cardiovascular drug design and QSAR techniques are helpful for the optimization of structural requirements for designing novel compounds.
Prafulla Choudhari, Manish Bhatia
doaj +1 more source