Results 111 to 120 of about 1,444,758 (235)

Molecular modelling studies on adamantane-based Ebola virus GP-1 inhibitors using docking, pharmacophore and 3D-QSAR

, 2019
The pathogenic Ebola virus (EBOV) causes a potential health risk and global spread. To date, few drugs are available for the treatment of Ebola virus disease (EVD) that allow researchers to use computational methods for designing potential drugs.
H.K. Chaudhari (6385988), S.N. Mali (6385985)   +1 more
core   +1 more source

QSAR of Clerodane Diterpenoids with Cytotoxic and Antitumoral Activity Against V-79 Cells

, 2015
This work deals with diterpenoids of the clerodane type, compounds isolated from the extracts of different plant organs from trees mainly of the Flacourtiaceae family.
Takahata, Y, Cramer, B
core   +1 more source

Quantitative structure-activity relationship and ADME prediction studies on series of spirooxindoles derivatives for anti-cancer activity against colon cancer cell line HCT-116

Heliyon
Forty-one derivatives of spirooxindoles, active against HCT-116 colon cancer cells, underwent pharmacophore-based 3D-QSAR analysis to understand their correlation with anti-cancer activity. The study identified a seven-point pharmacophore model (ADHHRRR1)
Sukhmeet Kaur, Jasneet Kaur, Bilal Ahmad Zarger, Nasarul Islam, Nazirah Mir   +4 more
doaj   +1 more source

3D-QSAR-based pharmacophore modelling of quinazoline derivatives for the identification of acetylcholinesterase inhibitors through virtual screening, molecular docking, molecular dynamics and DFT studies

Alzheimer’s disease (AD) is a progressive neurological disorder responsible for the cognitive dysfunction and cognitive impairment in the patients. Acetylcholinesterase inhibitors (AChEIs) are used to treat AD however, these only provided symptomatic ...
Vijay Kumar (377076), Kailash Jangid (13870205), Vinay Kumar (178313), Vinod Kumar (48743), Naveen Kumar (66313)   +4 more
core   +1 more source

[Video] Scientists turn to 3D technology to help restore Notre Dame

, 2021
"Scientists have enlisted the help of 3D imaging technology to restore Notre Dame to its former glory. A digital team from France's National Centre for Scientific Research has been working on the site for the past two years since the cathedral was ...
Consortium 3D SHS Team
core  

Development and validation of a 3D similarity method for virtual screening [PDF]

, 2013
A predictive 3D similarity workflow approach has been developed using a set of modular Java computer programs that implement algorithms that aim to capture the key components of a 3D similarity search and aim to incorporate methods that address both ...
Butler, Daniel
core   +1 more source

Archéologie :imagerie numérique et 3D

, 2018
Participation du CST3D SHS au séminaire scientifique organisé par l'IRISA /INRAP. Juin 2018 , Paris. Les communications du séminaire se sont concentrées sur les apports heuristiques de la modélisation 3D et de l’imagerie ...
Consortium 3D SHS Team
core  

Réaliser un projet de modèles numériques 3D pour le patrimoine. Guide de rédaction d'un cahier des charges

, 2020
"Dans le cadre des activités du Consortium 3D de la TGIR Huma-Num, de nombreuses rencontres ont eu lieu réunissant des spécialistes aux profils divers (historiens, archéologues, informaticiens, architectes, ingénieurs 3D, archivistes …etc.) afin de ...
Consortium 3D SHS Team
core  

Apport critique sur les matériels et logiciels 3D : Synthèse des outils et des technologies 3D

, 2020
"Le regroupement des différents partenaires du Consortium 3D SHS (Huma-Num) a été l’occasion de partager l’expertise et le savoir-faire - tant théorique que pratique - de ses membres, sur les modalités de production d’un objet numérique patrimonial.
Consortium 3D SHS Team
core  

Aïoli, une plateforme d'annotation sémantique 3D pour la documentation collaborative d'objets patrimoniaux

, 2020
"Modéliser puis annoter un objet patrimonial en 3D à l’aide d’un simple smartphone, c’est ce que permet aujourd’hui le web service Aïoli développé au sein du laboratoire MAP ...."
Consortium 3D SHS Team
core