Results 161 to 170 of about 1,883,863 (248)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Quantifying wheat spike morphology by high resolution 3D surface scanning. [PDF]

Plant Methods
Greche L, Virlet N, Hawkesford MJ.
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Virtual Patient-Specific 3-Dimensional Specimen Maps for Adjuvant Radiation Therapy Planning in Mucosal Head and Neck Squamous Cell Carcinoma. [PDF]

Adv Radiat Oncol
Jin W, Topf MC, Aweeda M, Prasad K, Prosak O, Sridhar S, Kohutek Z, All S, Kim DWN, Cmelak A, Whitaker R, Langerman A, Mannion K, Hicks M, Rohde S, Sinard R, Rosenthal E, Lockney NA.   +17 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

A pump-free microfluidic device for integrated multi-functional testing of tumor spheroids. [PDF]

APL Bioeng
Steinberg E, Azulay GD, de Villa AR, Schwob O, Benny O.   +4 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Role of Intraoperative 2D and 3D Fluoroscopy in Identifying Malposition of Screws in Surgical Fixation of Intra-articular Distal Radius Fractures in Comparison to Post-operative Computed Tomography. [PDF]

J Orthop Case Rep
Shah ZA, Nawaz A, Rathod R, Ghoneem M, Ashber I, Ismaily HA.   +5 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

SCAPULAR FRACTURES: COMPARISON OF GLENOPOLAR ANGLE MEASUREMENT USING 3D COMPUTED TOMOGRAPHY AND CONVENTIONAL RADIOGRAPHY. [PDF]

Acta Ortop Bras
Bonadiman JA, Minski PT, Appel FD, Bervian E, Piluski P, Lech O.   +5 more
europepmc   +1 more source