Results 121 to 130 of about 31,025 (283)

Preventing bacterial adhesion on scaffolds for bone tissue engineering [PDF]

, 2016
Bone implant infection constitutes a major sanitary concern which is associated to high morbidity and health costs. This manuscript focused on overviewing the main research efforts committed up to date to develop innovative alternatives to conventional ...
Colilla, Montserrat, Izquierdo-Barba, Isabel, Sánchez Salcedo, Sandra, Vallet Regí, María   +3 more
core   +2 more sources

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Kinetic Monte Carlo and Cellular Particle Dynamics Simulations of Multicellular Systems

, 2011
Computer modeling of multicellular systems has been a valuable tool for interpreting and guiding in vitro experiments relevant to embryonic morphogenesis, tumor growth, angiogenesis and, lately, structure formation following the printing of cell ...
Adrian Neagu, Bogdan Barz, Elijah Flenner, G. Forgacs, Gabor Forgacs, Ioan Kosztin, J. D. Eshelby, J. Frenkel, J. Israelachvili, Lorant Janosi, M. S. Steinberg, R. A. Foty   +11 more
core   +1 more source

The potential of additive manufacturing in the smart factory industrial 4.0: A review [PDF]

, 2019
Additive manufacturing (AM) or three-dimensional (3D) printing has introduced a novel production method in design, manufacturing, and distribution to end-users.
Dehghanghadikolaei, Amir, Emamian, Sattar S., Fotovvati, Behzad, Gisario, Annamaria, Mehrpouya, Mehrsha, Vosooghnia, Alireza   +5 more
core   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

3D bioprinting of novel biocompatible scaffolds for endothelial cell repair [PDF]

, 2019
The aim of this study was to develop and evaluate an optimized 3D bioprinting technology in order to fabricate novel scaffolds for the application of endothelial cell repair.
Ali Nokhodchi, Amit, Dragun, Gordon Ferns, Khong, Lamia Heikal, Maniruzzaman, Mohammed Maniruzzaman, Pietro Ghezzi, Yan Wu   +9 more
core   +1 more source

3D Bioprinting for Organ Regeneration

Advanced Healthcare Materials, 2016
Regenerative medicine holds the promise of engineering functional tissues or organs to heal or replace abnormal and necrotic tissues/organs, offering hope for filling the gap between organ shortage and transplantation needs. Three‐dimensional (3D) bioprinting is evolving into an unparalleled biomanufacturing technology due to its high‐integration ...
Haitao, Cui, Margaret, Nowicki, John P, Fisher, Lijie Grace, Zhang   +3 more
openaire   +3 more sources

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Spheroid-Exosome-Based Bioprinting Technology in Regenerative Medicine

Journal of Functional Biomaterials
Since the discovery that exosomes can exchange genes, their potential use as tools for tissue regeneration, disease diagnosis, and therapeutic applications has drawn significant attention.
Hwa-Yong Lee, Jin Woo Lee
doaj   +1 more source