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Strategies to Improve Nanofibrous Scaffolds for Vascular Tissue Engineering
The biofabrication of biomimetic scaffolds for tissue engineering applications is a field in continuous expansion. Of particular interest, nanofibrous scaffolds can mimic the mechanical and structural properties (e.g., collagen fibers) of the natural ...
Yao, Tianyu +7 more
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Novel Molecule Nell-1 Promotes the Angiogenic Differentiation of Dental Pulp Stem Cells
IntroductionThis work aimed to reveal the crucial role of Nell-1 in the angiogenic differentiation of human dental pulp stem cells (DPSCs) alone or co-cultured with human umbilical vein endothelial cell (HUVECs) in vitro and whether this molecule is ...
Mengyue Li +9 more
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Silica–gelatin hybrids for tissue regeneration : inter-relationships between the process variables [PDF]
Owing to their diverse range of highly tailorable material properties, inorganic/organic hybrids have the potential to meet the needs of biodegradable porous scaffolds across a range of tissue engineering applications.
Mark E. Smith +14 more
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Towards clinical translation of upscaled osteogenic grafts using human adipose tissue progenitors [PDF]
Tissue engineering is an emerging strategy in medical field that focuses on regeneration or replacement of lost or damaged tissue and organs. Most of the tissues in human body have no or limited self renewal and regeneration potential which decrease with
Güven, Sinan
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Glycosaminoglycans: From Vascular Physiology to Tissue Engineering Applications
Cardiovascular diseases represent the number one cause of death globally, with atherosclerosis a major contributor. Despite the clinical need for functional arterial substitutes, success has been limited to arterial replacements of large-caliber vessels (
Moroni, Lorenzo +7 more
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Fusobacterium nucleatum (F. nucleatum) is an early pathogenic colonizer in periodontitis, but the host response to infection with this pathogen remains unclear. In this study, we built an F. nucleatum infectious model with human periodontal ligament stem
Yushang Wang +10 more
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Engineering Niches for Bone Tissue Regeneration
This chapter places the topics from previous chapters into the context of bone tissue regeneration. The chapter introduces bone as a tissue and as a complex organ and discusses the clinical need for bone regeneration strategies.
Habibovic, Pamela; id_orcid +6 more
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Nerve commitment in Hydra. I. Role of morphogenetic signals [PDF]
The kinetics of nerve commitment during head regeneration in Hydra were investigated using a newly developed assay for committed cells. Committed nerve precursors were assayed by their ability to continue nerve differentiation following explanation of ...
Venugopal, G., David, Charles N.
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p53, the major tumor suppressor, is frequently mutated in many cancers, and up to 84% of human melanomas harbor wild-type p53, which is considered to be an ideal target for melanoma therapy.
Jie Wen +11 more
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Background Stem cells from apical papilla (SCAP) located in the root apex of immature permanent teeth are a reliable cell source for pulp-dentine complex regeneration.
Jing Du +7 more
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