Results 41 to 50 of about 5,446,723 (211)

Microvesicles as Mediators of Tissue Regeneration [PDF]

Translational Research, 2014
The use of stem cells in the treatment of various diseases and injuries has received increasing interest during the past decade. Injected stem cells, such as mesenchymal stem cells, stimulate tissue repair largely through the secretion of soluble factors that regulate various processes of tissue regeneration, including inflammatory responses, apoptosis,
Keith, Sabin, Nobuaki, Kikyo
openaire   +2 more sources

Study of the inflammatory activating process in the early stage of Fusobacterium nucleatum infected PDLSCs

International Journal of Oral Science, 2023
Fusobacterium nucleatum (F. nucleatum) is an early pathogenic colonizer in periodontitis, but the host response to infection with this pathogen remains unclear. In this study, we built an F. nucleatum infectious model with human periodontal ligament stem
Yushang Wang, Lihua Wang, Tianyong Sun, Song Shen, Zixuan Li, Xiaomei Ma, Xiufeng Gu, Xiumei Zhang, Ai Peng, Xin Xu, Qiang Feng   +10 more
doaj   +1 more source

3D Electrospun Synthetic Extracellular Matrix for Tissue Regeneration

Small Science, 2021
Electrospinning is considered the most versatile micro‐/nanofiber fabrication technology. The electrospun fibers hold high surface area, desired mechanical properties, controlled topography, as well as the ease of biochemical functionalization.
Yingchun Su, Mette Steen Toftdal, Alice Le Friec, M. Dong, Xiaojun Han, Menglin Chen   +5 more
semanticscholar   +1 more source

Microenvironment-responsive nanomedicines: a promising direction for tissue regeneration

Military Medical Research
Severe tissue defects present formidable challenges to human health, persisting as major contributors to mortality rates. The complex pathological microenvironment, particularly the disrupted immune landscape within these defects, poses substantial ...
Yuan Xiong, Bobin Mi, Mohammad-Ali Shahbazi, Tian Xia, Jun Xiao   +4 more
semanticscholar   +1 more source

Advances in mesenchymal stem cell conditioned medium-mediated periodontal tissue regeneration

Journal of Translational Medicine, 2021
Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and hard periodontal tissues. Complete periodontal regeneration in clinics using the currently available treatment approaches is still a challenge.
Hongbing Lin, Huishan Chen, Xuetao Zhao, Zhen Chen, Peipei Zhang, Yue Tian, Yawei Wang, Tong Ding, Lijing Wang, Yuqin Shen   +9 more
semanticscholar   +1 more source

Bone Tissue Engineering and Regeneration [PDF]

BioMed Research International, 2014
Bone tissue engineering and regeneration constitutes a burgeoning new area of investigation, incorporating scientists, engineers, and clinicians with diverse academic backgrounds. With an aging global population, the need to engineer and regenerate mesenchymal tissues becomes even more pressing.
Levi, Benjamin, Péault, Bruno, James, Aaron W   +2 more
openaire   +2 more sources

A carbazole compound, 9-ethyl-9H-carbazole-3-carbaldehyde, plays an antitumor function through reactivation of the p53 pathway in human melanoma cells

Cell Death and Disease, 2021
p53, the major tumor suppressor, is frequently mutated in many cancers, and up to 84% of human melanomas harbor wild-type p53, which is considered to be an ideal target for melanoma therapy.
Jie Wen, Wenqian Chen, Baoxiang Zhao, Qiuping Xu, Chang Liu, Qun Zhang, Zhiwei Xie, Yonggan Yan, Jing Guo, Jun Huang, Junying Miao, Xunwei Wu   +11 more
doaj   +1 more source

Macrophage plasticity: signaling pathways, tissue repair, and regeneration

MedComm
Macrophages are versatile immune cells with remarkable plasticity, enabling them to adapt to diverse tissue microenvironments and perform various functions.
Lingfeng Yan, Jue Wang, Xin Cai, Y. Liou, Hanming Shen, Jianlei Hao, Canhua Huang, Gaoxing Luo, Weifeng He   +8 more
semanticscholar   +1 more source

Barrier membranes for tissue regeneration in dentistry

Biomaterial Investigations in Dentistry, 2021
Background: In dentistry, barrier membranes are used for guided tissue regeneration (GTR) and guided bone regeneration (GBR). Various membranes are commercially available and extensive research and development of novel membranes have been conducted.
J. Sasaki, G. L. Abe, Aonan Li, P. Thongthai, R. Tsuboi, T. Kohno, S. Imazato   +6 more
semanticscholar   +1 more source

Decellularized Tissue for Muscle Regeneration [PDF]

International Journal of Molecular Sciences, 2018
Several acquired or congenital pathological conditions can affect skeletal muscle leading to volumetric muscle loss (VML), i.e., an irreversible loss of muscle mass and function. Decellularized tissues are natural scaffolds derived from tissues or organs, in which the cellular and nuclear contents are eliminated, but the tridimensional (3D) structure ...
Urciuolo A., De Coppi P.
openaire   +3 more sources