Results 61 to 70 of about 2,574,116 (304)
MicroRNAs Regulating Hippo-YAP Signaling in Liver Cancer
Biomedicines, 2021 Liver cancer is one of the most common cancers worldwide, and its prevalence and mortality rate are increasing due to the lack of biomarkers and effective treatments.
Na-Hyun Lee, So Jung Kim, Jeongeun Hyun
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
l-cysteine-modified chiral gold nanoparticles promote periodontal tissue regeneration
, 2021 Gold nanoparticles (AuNPs) with surface-anchored molecules present tremendous potential in tissue regeneration. However, little is known about chiral-modified AuNPs.
Kong, Na +17 more
core +1 more source
Stem Cell Research & Therapy, 2020 Background Periodontal ligament stem cells (PDLSCs) have many applications in the field of cytotherapy, tissue engineering, and regenerative medicine.
Xiaoyu Li +6 more
doaj +1 more source
Tissue Engineering for Meniscus Regeneration [PDF]
, 2010 Objective: Meniscus regeneration is limited, moreover, loss of meniscal tissue leads to osteoarthritis. A new biomaterial, consisting of hyaluronic acid and polycaprolactone was applied as a meniscus substitute device in a study in sheep. Methods: 24 sheep received a total medial meniscal replacement.
KON, ELIZAVETA +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Unravelling the mechanisms behind periosteal regeneration and its application in bone tissue engineering [PDF]
, 2017 This thesis explored the mechanisms underlying the structure and function of the periosteum in bone homeostasis and repair. The knowledge gained from these studies was then applied to the development of both a new tissue-engineered periosteal construct ...
Baldwin, Jeremy G.
core +1 more source
Nanotechnology in the Regeneration of Complex Tissues [PDF]
Bone and Tissue Regeneration Insights, 2014 Modern medicine faces a growing crisis as demand for organ transplantations continues to far outstrip supply. By stimulating the body's own repair mechanisms, regenerative medicine aims to reduce demand for organs, while the closely related field of tissue engineering promises to deliver “of-the-self” organs grown from patients' own stem cells to ...
openaire +4 more sources
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source