Results 61 to 70 of about 5,446,723 (211)

Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Materials Today Bio, 2022
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles secreted by cells that play important biological roles. Mesenchymal stem cells are a class of cells with the potential for self-healing and multidirectional ...
Yikun Ju, Yue Hu, Pu Yang, Xiaoyan Xie, B. Fang   +4 more
semanticscholar   +1 more source

Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration

Nano-Micro Letters
Highlights Nanozyme-based approaches to produce therapeutic hydrogels. Enzymatic mechanisms and multifunctional roles of nanozyme-engineered hydrogels for skin therapy.
Amal George Kurian, Rajendra K. Singh, Varsha Sagar, Jung-Hwan Lee, Hae-Won Kim   +4 more
doaj   +1 more source

An in situ tissue engineering scaffold with growth factors combining angiogenesis and osteoimmunomodulatory functions for advanced periodontal bone regeneration

Journal of Nanobiotechnology, 2021
Background The regeneration of periodontal bone defect remains a vital clinical challenge. To date, numerous biomaterials have been applied in this field. However, the immune response and vascularity in defect areas may be key factors that are overlooked
Tian Ding, Wenyan Kang, Jianhua Li, Lu Yu, Shaohua Ge   +4 more
doaj   +1 more source

Tissue Engineering for Meniscus Regeneration [PDF]

, 2010
Objective: Meniscus regeneration is limited, moreover, loss of meniscal tissue leads to osteoarthritis. A new biomaterial, consisting of hyaluronic acid and polycaprolactone was applied as a meniscus substitute device in a study in sheep. Methods: 24 sheep received a total medial meniscal replacement.
KON, ELIZAVETA, Delcogliano M, FILARDO, GIUSEPPE, Peretti G, Di Martino A, MARCACCI, MAURILIO   +5 more
openaire   +3 more sources

MicroRNAs Regulating Hippo-YAP Signaling in Liver Cancer

Biomedicines, 2021
Liver cancer is one of the most common cancers worldwide, and its prevalence and mortality rate are increasing due to the lack of biomarkers and effective treatments.
Na-Hyun Lee, So Jung Kim, Jeongeun Hyun
doaj   +1 more source

Synergistic protective and regenerative effects of hyaluronic acid and polynucleotides against UVA-induced oxidative stress in dermal fibroblasts

Scientific Reports
Ultraviolet A (UVA) radiation, a principal driver of skin photoaging, generates excessive reactive oxygen species (ROS) in dermal fibroblasts, causing oxidative stress, loss of viability, inflammatory signaling, and extracellular matrix (ECM) degradation.
Trang Thanh Thien Tran, Soon Chul Heo, Jun Hee Lee, Hae-Won Kim   +3 more
doaj   +1 more source

A high-glucose diet affects Achilles tendon healing in rats

Scientific Reports, 2017
Chronic and acute tendinopathies are difficult to treat and tendon healing is generally a very slow and incomplete process and our general understanding of tendon biology and regeneration lags behind that of muscle or bone.
Stefanie Korntner, Nadja Kunkel, Christine Lehner, Renate Gehwolf, Andrea Wagner, Peter Augat, Daniel Stephan, Verena Heu, Hans-Christian Bauer, Andreas Traweger, Herbert Tempfer   +10 more
doaj   +1 more source

The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells

Stem Cell Research & Therapy, 2020
Background Periodontal ligament stem cells (PDLSCs) have many applications in the field of cytotherapy, tissue engineering, and regenerative medicine.
Xiaoyu Li, Bowen Zhang, Hong Wang, Xiaolu Zhao, Zijie Zhang, Gang Ding, Fulan Wei   +6 more
doaj   +1 more source

Nanotechnology in the Regeneration of Complex Tissues [PDF]

Bone and Tissue Regeneration Insights, 2014
Modern medicine faces a growing crisis as demand for organ transplantations continues to far outstrip supply. By stimulating the body's own repair mechanisms, regenerative medicine aims to reduce demand for organs, while the closely related field of tissue engineering promises to deliver “of-the-self” organs grown from patients' own stem cells to ...
openaire   +4 more sources

Temporal transcriptome highlights the involvement of cytokine/JAK/STAT3 signaling pathway in the osteoinduction of BMSCs

Journal of Orthopaedic Surgery and Research, 2023
Background Mesenchymal stem cells (MSCs)-based therapy offers an effective strategy for bone regeneration to solve the clinical orthopedic problems. However, the transcriptional regulation of multiple transitional stages of continuous osteogenesis from ...
Xiao Ru, Peian Cai, Manli Tan, Li Zheng, Zhenhui Lu, Jinmin Zhao   +5 more
doaj   +1 more source