Results 21 to 30 of about 702,874 (310)
Stem Cells International, 2023 Blood-brain barrier (BBB) is the most important component of central nervous system (CNS) to keep toxins and pathogens from CNS. Although our studies demonstrated that using interleukin-6 antibodies (IL-6-AB) reversed the increased permeability of BBB ...
Jie Yang +9 more
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Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo. [PDF]
, 2009 BackgroundProstate stem/progenitor cells function in glandular development and maintenance. They may be targets for tumor initiation, so characterization of these cells may have therapeutic implications.
Garraway, Isla P +11 more
core +1 more source
Tissue Regeneration in Dentistry [PDF]
International Journal of Dentistry, 2012 Recently, various studies for tissue engineering have been conducted successfully to explore a new era of tissue defect treatment. To this end, three essential factors were examined extensively, that is, cells to be transplanted, signaling molecules, and scaffold. Currently, undifferentiated mesenchymal stem cells (MSCs) or the differentiated forms are
Kazuo Tanne +4 more
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Novel Molecule Nell-1 Promotes the Angiogenic Differentiation of Dental Pulp Stem Cells
Frontiers in Physiology, 2021 IntroductionThis work aimed to reveal the crucial role of Nell-1 in the angiogenic differentiation of human dental pulp stem cells (DPSCs) alone or co-cultured with human umbilical vein endothelial cell (HUVECs) in vitro and whether this molecule is ...
Mengyue Li +9 more
doaj +1 more source
Protein transduction: A novel tool for tissue regeneration [PDF]
, 2002 Tissue regeneration in humans is limited and excludes vitals organs like heart and brain. Transformation experiments with oncogenes like T antigen have shown that retrodifferentiation of the respective cells is possible but hard to control. To bypass the
Derer W. +4 more
core +1 more source
Bone Tissue Engineering and Regeneration [PDF]
BioMed Research International, 2014 Bone tissue engineering and regeneration constitutes a burgeoning new area of investigation, incorporating scientists, engineers, and clinicians with diverse academic backgrounds. With an aging global population, the need to engineer and regenerate mesenchymal tissues becomes even more pressing.
Levi, Benjamin +2 more
openaire +3 more sources
Decellularized Tissue for Muscle Regeneration [PDF]
International Journal of Molecular Sciences, 2018 Several acquired or congenital pathological conditions can affect skeletal muscle leading to volumetric muscle loss (VML), i.e., an irreversible loss of muscle mass and function. Decellularized tissues are natural scaffolds derived from tissues or organs, in which the cellular and nuclear contents are eliminated, but the tridimensional (3D) structure ...
Urciuolo A., De Coppi P.
openaire +3 more sources
International Journal of Oral Science, 2023 Fusobacterium nucleatum (F. nucleatum) is an early pathogenic colonizer in periodontitis, but the host response to infection with this pathogen remains unclear. In this study, we built an F. nucleatum infectious model with human periodontal ligament stem
Yushang Wang +10 more
doaj +1 more source
3D Printed TCP-Based Scaffold Incorporating VEGF-Loaded PLGA Microspheres for Craniofacial Tissue Engineering [PDF]
, 2017 Objective Vascularization is a critical process during bone regeneration/repair and the lack of tissue vascularization is recognized as a major challenge in applying bone tissue engineeringmethods for cranial and maxillofacial surgeries.
D. Lobner +7 more
core +2 more sources
Cell Death and Disease, 2021 p53, the major tumor suppressor, is frequently mutated in many cancers, and up to 84% of human melanomas harbor wild-type p53, which is considered to be an ideal target for melanoma therapy.
Jie Wen +11 more
doaj +1 more source