Results 51 to 60 of about 15,296 (229)

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang   +7 more
wiley   +1 more source

Point-of-care additive manufacturing: state of the art and adoption in Spanish hospitals during pre to post COVID-19 era

open access: yes3D Printing in Medicine
Background 3D technologies [Virtual and Augmented 3D planning, 3D printing (3DP), Additive Manufacturing (AM)] are rapidly being adopted in the healthcare sector, demonstrating their relevance in personalized medicine and the rapid development of medical
Arnau Valls-Esteve   +8 more
doaj   +1 more source

Application of Hydrogels as Three-Dimensional Bioprinting Ink for Tissue Engineering

open access: yesGels, 2023
The use of three-dimensional bioprinting technology combined with the principle of tissue engineering is important for the construction of tissue or organ regeneration microenvironments. As a three-dimensional bioprinting ink, hydrogels need to be highly
Mengbo Xie   +4 more
doaj   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

open access: yesAdvanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez   +8 more
wiley   +1 more source

Bioprinting on Organ-on-Chip: Development and Applications

open access: yesBiosensors, 2022
Organs-on-chips (OoCs) are microfluidic devices that contain bioengineered tissues or parts of natural tissues or organs and can mimic the crucial structures and functions of living organisms.
Maria Anna Chliara   +2 more
doaj   +1 more source

3D Bioprinting of Glioblastoma Model

open access: yesJournal of 3D Printing in Medicine, 2020
The most common and malignant primary brain tumor in adults is glioblastoma (GBM). In vitro 3D brain models are needed to better understand the pathological processes underlying GBM and ultimately develop more efficient antineoplastic agents. Here, we describe the bioprinting methods that have been used to fabricate volumetric GBM models.
Carolina Parra-Cantu   +3 more
openaire   +3 more sources

3D bioprinting for modelling vasculature [PDF]

open access: yesMicrophysiological Systems, 2018
Though in vivo models provide the most physiologically-relevant environment for studying tissue development and function, an in vitro substitute is being offered by the advancement of three-dimensional (3D) bioprinting technology, which is a reproducible and scalable fabrication strategy providing precise 3D control compared to conventional ...
Pranabesh, Sasmal   +3 more
openaire   +2 more sources

3D Bioprinted Breast Cancer‐Stroma Model with Tailored Migration‐Permissive Bioink Reveals Impact of Adipose‐Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics

open access: yesAdvanced Healthcare Materials, EarlyView.
A migration‐permissive bioink composed of methacrylated collagen type I and thiolated hyaluronic acid enables 3D bioprinting of breast cancer‐stroma models. Single‐cell tracking reveals that adipose stromal cells enhance tumor cell motility and stromal invasion, accompanied by collagen remodeling, and a shift in tumor cell morphology.
Sabrina Stecher   +19 more
wiley   +1 more source

Biomaterials Based on Marine Resources for 3D Bioprinting Applications

open access: yesMarine Drugs, 2019
Three-dimensional (3D) bioprinting has become a flexible tool in regenerative medicine with potential for various applications. Further development of the new 3D bioprinting field lies in suitable bioink materials with satisfied printability, mechanical ...
Yi Zhang   +6 more
doaj   +1 more source

Structural Guidance in 3D Microgel‐in‐Hydrogel Systems to Improve Chondrogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
The Anisogel, an anisotropic microgel‐in‐hydrogel system, guides chondrogenic differentiation of human mesenchymal stromal cells (hMSCs) modulated by the alignment and size of anisometric microgels. Chondrogenic markers are upregulated in an in vitro model and guided tissue infiltration is enhanced in a semi‐orthopedic mouse model due to the physico ...
Julia Kamp   +12 more
wiley   +1 more source

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