Results 61 to 70 of about 1,426,315 (259)

Bioprinting of multimaterials with computer-aided design/computer-aided manufacturing

, 2020
Multimaterials deposition, a distinct advantage in bioprinting, overcomes material's limitation in hydrogel-based bioprinting. Multimaterials are deposited in a build/support configuration to improve the structural integrity of three-dimensional ...
Yeong, Wai Yee, Sing, Swee Leong, J. M. Lee, W. Y. Yeong, S. L. Sing, Lee, Jia Min   +5 more
core   +1 more source

Design aspects and characterization of hydrogel-based bioinks for extrusion-based bioprinting

, 2023
3D-bioprinting has become a valid technique for tissue and organ regeneration, as the printing of living cells is allowed while the hydrogel-based ink material provides them mechanical and structural support. Self-healing shear-thinning hydrogel inks can
Minna Kellomäki, Kellomäki, Minna, Jennika Karvinen, Karvinen, Jennika   +3 more
core   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

Application of Hydrogels as Three-Dimensional Bioprinting Ink for Tissue Engineering

Gels, 2023
The use of three-dimensional bioprinting technology combined with the principle of tissue engineering is important for the construction of tissue or organ regeneration microenvironments. As a three-dimensional bioprinting ink, hydrogels need to be highly
Mengbo Xie, Jingjing Su, Shengxi Zhou, Jingan Li, Kun Zhang   +4 more
doaj   +1 more source

Hybrid three-dimensional (3D) bioprinting of retina equivalent for ocular research

, 2017
In this article, a hybrid retina construct was created via three-dimensional (3D) bioprinting technology. The construct was composed of a PCL ultrathin membrane, ARPE-19 cell monolayer and Y79 cell-laden alginate/pluronic bioink.
Yeong, Wai Yee, Tan, Edgar Yong Sheng, Augustinus Laude, Laude, Augustinus, Shi, Pujiang, Tan Yong Sheng Edgar, Pujiang Shi, Wai Yee Yeong   +7 more
core   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Recapitulating gestational progression: a high-throughput 3D bioprinted vascularized human placenta demonstrating stage-specific molecular and functional signatures of human pregnancy

Scientific Reports
The placenta is a highly dynamic organ that supports the growth and development of the fetus during gestation. Malfunction of the placenta causes disorders of the pregnancy, including preeclampsia and pre-term birth.
Cristina Antich, Yu-Chi Chen, Justine Noel, Yanyan Qu, Yuhong Fang, Shayne Frebert, Dingyin Tao, Lauren S. Richardson, Ramkumar Menon, Min Jae Song, Marc Ferrer   +10 more
doaj   +1 more source

Bioprinting on Organ-on-Chip: Development and Applications

Biosensors, 2022
Organs-on-chips (OoCs) are microfluidic devices that contain bioengineered tissues or parts of natural tissues or organs and can mimic the crucial structures and functions of living organisms.
Maria Anna Chliara, Stavroula Elezoglou, Ioanna Zergioti   +2 more
doaj   +1 more source

Engineering bioinks for 3D bioprinting

Biofabrication, 2021
Abstract In recent years, three-dimensional (3D) bioprinting has attracted wide research interest in biomedical engineering and clinical applications. This technology allows for unparalleled architecture control, adaptability and repeatability that can overcome the limits of conventional biofabrication techniques.
Guy Decante, João B Costa, Joana Silva-Correia, Maurice N Collins, Rui L Reis, J Miguel Oliveira   +5 more
openaire   +2 more sources

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source