Results 51 to 60 of about 19,563 (241)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Graph-Based Construction of 3D Korean Giwa House Models

open access: yesBuildings, 2019
This paper proposes a graph-based algorithm for constructing 3D Korean traditional houses automatically using a computer graphics technique. In particular, we target designing the most popular traditional house type, a giwa house, whose roof is covered ...
Mankyu Sung
doaj   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

A survey of image-based few-shot 3D reconstruction

open access: yes智能科学与技术学报, 2022
Few-shot 3D reconstruction is considered one of the classic applications of the third generation of artificial intelligence.In the area of computer graphics and computer vision, few-shot 3D reconstruction has attracted the attention of many researchers ...
Hang YU   +3 more
doaj  

Three-dimensional imaging and scanning: Current and future applications for pathology

open access: yesJournal of Pathology Informatics, 2017
Imaging is vital for the assessment of physiologic and phenotypic details. In the past, biomedical imaging was heavily reliant on analog, low-throughput methods, which would produce two-dimensional images.
Navid Farahani   +7 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

DESIGN BY LINES - STUDY ON AN EDUCATIONAL METHOD FOR ARCHITECTURAL FORM GENERATION

open access: yesJournal of Industrial Design and Engineering Graphics, 2007
This study examines the effectiveness of our computer graphics education package named “Design by Lines”, which we have developed for our Descriptive and Geometry education in Architectural department.
ANDO Naomi   +2 more
doaj  

Archeologia virtuale, realismo, interattività e performance: dalla ricostruzione alla fruizione on line

open access: yesDisegnare con, 2011
L'articolo presenta le diverse fasi di un progetto di archeologia virtuale, nel quale i diversi tipi di dati vengono acquisiti e realizzati utilizzando approcci metodologici diversi, per poi essere integrati all'interno di un unico ambiente interattivo ...
Sofia Pescarin   +4 more
doaj   +1 more source

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