Results 81 to 90 of about 725,079 (307)
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
3D geometry. A proposal to integrate computer graphics in descriptive geometry
Revista de Expresión Gráfica en la Edificación, 2016 El presente artículo se centra en el estudio de la integración de los programas de informática gráfica en la didáctica de la Geometría Descriptiva y los nuevos planteamientos que pueden aportar a esta disciplina.
Javier Pita Andreu
doaj +1 more source
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
3D Face Geometry Optimization Using Artificial Intelligence and Computer Graphics [PDF]
, 2022 Dan Liu
openalex +1 more source
Study of 3D Technologies for Web
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2019 This paper presents solutions for objectives and presentation related to 3D technology exploration and three-dimensional web visualization, implementation of approaches for 3D reconstruction of museum exhibits, creation of models for three-dimensional ...
Pavel Hristov, Emiliyan Petkov
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Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Three-dimensional imaging and scanning: Current and future applications for pathology
Journal of Pathology Informatics, 2017 Imaging is vital for the assessment of physiologic and phenotypic details. In the past, biomedical imaging was heavily reliant on analog, low-throughput methods, which would produce two-dimensional images.
Navid Farahani +7 more
doaj +1 more source
A Benchmarking Framework for Interactive 3D Applications in the Cloud [PDF]
arXiv, 2020 With the growing popularity of cloud gaming and cloud virtual reality (VR), interactive 3D applications have become a major type of workloads for the cloud. However, despite their growing importance, there is limited public research on how to design cloud systems to efficiently support these applications, due to the lack of an open and reliable ...
arxiv
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
A survey of image-based few-shot 3D reconstruction
智能科学与技术学报, 2022 Few-shot 3D reconstruction is considered one of the classic applications of the third generation of artificial intelligence.In the area of computer graphics and computer vision, few-shot 3D reconstruction has attracted the attention of many researchers ...
Hang YU +3 more
doaj