3D imaging lipidometry in single cell by in-flow holographic tomography
Opto-Electronic Advances, 2023 The most recent discoveries in the biochemical field are highlighting the increasingly important role of lipid droplets (LDs) in several regulatory mechanisms in living cells.
Daniele Pirone +12 more
doaj +1 more source
Experimental Results of a 3D Millimeter-Wave Compressive-Reflector-Antenna Imaging System
, 2018 This letter presents the first experimental results of our three-dimensional (3D) millimeter-wave (mm-wave) Compressive-Reflector-Antenna (CRA) imaging system.
Bisulco, A. +7 more
core +1 more source
Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND) [PDF]
, 2018 A key challenge in medical imaging is determining a precise correspondence between image properties and tissue microstructure. This comparison is hindered by disparate scales and resolutions between medical imaging and histology.
Ball, G +6 more
core +6 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
3D tomography of cells in micro-channels [PDF]
, 2017 We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far been limited to
Christ, A. F. +6 more
core +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Deep-prior ODEs augment fluorescence imaging with chemical sensors
Nature CommunicationsTo study biological signalling, great effort goes into designing sensors whose fluorescence follows the concentration of chemical messengers as closely as possible.
Thanh-an Pham +4 more
doaj +1 more source
Diattenuation of Brain Tissue and its Impact on 3D Polarized Light Imaging
, 2017 3D-Polarized Light Imaging (3D-PLI) reconstructs nerve fibers in histological brain sections by measuring their birefringence. This study investigates another effect caused by the optical anisotropy of brain tissue - diattenuation. Based on numerical and
Amunts, Katrin +5 more
core +1 more source
Simultaneous multiplane imaging with reverberation multiphoton microscopy [PDF]
, 2019 Multiphoton microscopy (MPM) has gained enormous popularity over the years for its capacity to provide high resolution images from deep within scattering samples1.
Beaulieu, Devin R. +4 more
core +1 more source