Results 151 to 160 of about 3,343,678 (291)

Embryotoxicity and mixture effects of legacy PFAS in a human iPSC-based 3D model. [PDF]

Cell Biol Toxicol
Treschow AF, Martiny E, Gutierrez CT, Niklas AA, Scholze M, Vinggaard AM, Valente MJ.   +6 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Scaling deep learning for material imaging with a pseudo 3D model for domain transfer. [PDF]

Nat Commun
Tang K, Armstrong RT, Mostaghimi P, Niu Y, Meyer Q, Zhao C, Finegan DP, Popeil M, Singh K, Menke H, Dimou AP, Bultreys T, Mascini A, Knackstedt M, Da Wang Y.   +14 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Heterotypic 3D Model of Breast Cancer Based on Tumor, Stromal and Endothelial Cells: Cytokines Interaction in the Tumor Microenvironment. [PDF]

Cells
Leonteva A, Kazakova A, Berezutskaya E, Ilyina A, Sergeevichev D, Vladimirov S, Bogachek M, Vakhrushev I, Makarevich P, Richter V, Nushtaeva A.   +10 more
europepmc   +1 more source

3D modelling

Estimate of necessity of 3D (versus current 1D) chemical and dynamical atmospheric models in the interpretation of transit, eclipse and phase-curves observations, the outcome will be used by WP3.
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Targeting Cell-Matrix Induced Chemoresistance With Regorafenib in a 3D Model of Osteosarcoma. [PDF]

J Biomed Mater Res A
Rao RR, Huang MS, Zhang D, Huerta-López C, Long C, Rodriguez GA, Mozipo EAT, Sagi S, Heilshorn SC.   +8 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Commentary on "3D Model for BPPV Diagnosis and Treatment. [PDF]

Turk Arch Otorhinolaryngol
Çakır M, Özdoğan F, Özel HE.
europepmc   +1 more source